SLC7A8 产品
(Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
Categories
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).
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Featured SLC7A8 Categories
Recommended SLC7A8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, IHC (p), IF, IP
Validations
- (5)
Cat. No.
ABIN1500960
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN6243302
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN525163
Quantity
100 μg
Datasheet
Datasheet
Recommended SLC7A8 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320534
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320533
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118920
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SLC7A8 Products
: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." in: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).: "Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma." in: Brain tumor pathology, Vol. 34, Issue 4, pp. 179-181, (2018) (PubMed).
: "Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc, a System L Amino Acid Transporter." in: International journal of molecular sciences, Vol. 18, Issue 8, (2018) (PubMed).
: "Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 1, pp. 129-137, (2016) (PubMed).
Synonyms and alternative names related to SLC7A8
solute carrier family 7 member 8 (SLC7A8), solute carrier family 7 member 8 (Slc7a8), solute carrier family 7 member 8 L homeolog (slc7a8.L), solute carrier family 7 member 8 (slc7a8), solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b), 4F2LC-5, AA408822, LAT2, Lat2, lat2, Lat4, LPI-PC1, lpi-pc1, si:ch211-14a17.3, si:zc14a17.3, slc7a8, XAA2Protein level used designations for SLC7A8
- L-type amino acid transporter 2
- integral membrane protein E16H
- large neutral amino acids transporter small subunit 2
- solute carrier family 7 (amino acid transporter, L-type), member 8
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
- cationic amino acid transporter y+ system
- solute carrier family 7 member 8
- glycoprotein-associated amino acid transporter LAT2
- 4F2-LC5
- mLAT2
- solute carrier family 8 (cationic amino acid transporter, y+ system), member 7
- solute carrier family 7 (amino acid transporter light chain, L system), member 8
- zmp:0000000645
- zmp:0000000781
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