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SLC6A3 产品

(Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

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This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009].

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Featured SLC6A3 Categories

SLC6A3 抗体

High quality antibodies with extensive validation data.

SLC6A3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SLC6A3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC6A3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7270474
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN733373
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN520246
Quantity 100 μg
Datasheet Datasheet

Recommended SLC6A3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970352
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970351
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962871
Quantity 96 tests
Datasheet Datasheet

Recommended SLC6A3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320507
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320506
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394450
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SLC6A3 Products

Nguyen, Vemaraju, Nayak, Odaka, Buhr, Alonzo, Tran, Batie, Upton, Darvas, Kozmik, Rao, Hegde, Iuvone, Van Gelder, Lang: "An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye." in: Nature cell biology, Vol. 21, Issue 4, pp. 420-429, (2019) (PubMed).

Carballo-Carbajal, Laguna, Romero-Giménez, Cuadros, Bové, Martinez-Vicente, Parent, Gonzalez-Sepulveda, Peñuelas, Torra, Rodríguez-Galván, Ballabio, Hasegawa, Bortolozzi, Gelpi, Vila: "Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis." in: Nature communications, Vol. 10, Issue 1, pp. 973, (2019) (PubMed).

Wiers, Lohoff, Lee, Muench, Freeman, Zehra, Marenco, Lipska, Auluck, Feng, Sun, Goldman, Swanson, Wang, Volkow: "Methylation of the dopamine transporter gene in blood is associated with striatal dopamine transporter availability in ADHD: A preliminary study." in: The European journal of neuroscience, Vol. 48, Issue 3, pp. 1884-1895, (2018) (PubMed).

Romei, Bonifacino, Milanese, Usai, Raiteri: "Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission." in: Brain research bulletin, Vol. 127, pp. 100-110, (2016) (PubMed).

Qian, Cai, Wang, Zhang, Zhao, Qian, Yang, Liu, Hasegawa: "Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats." in: Yonago acta medica, Vol. 59, Issue 2, pp. 100-10, (2016) (PubMed).

Varner, Jaquins-Gerstl, Michael: "Enhanced Intracranial Microdialysis by Reduction of Traumatic Penetration Injury at the Probe Track." in: ACS chemical neuroscience, Vol. 7, Issue 6, pp. 728-36, (2016) (PubMed).

Romanov, Zeisel, Bakker, Girach, Hellysaz, Tomer, Alpár, Mulder, Clotman, Keimpema, Hsueh, Crow, Martens, Schwindling, Calvigioni, Bains, Máté, Szabó, Yanagawa, Zhang, Rendeiro, Farlik, Uhlén, Wulff et al.: "Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes. ..." in: Nature neuroscience, Vol. 20, Issue 2, pp. 176-188, (2016) (PubMed).

Aher, Subramaniyan, Shanmugasundaram, Sase, Saroja, Holy, Höger, Beryozkina, Sitte, Leban, Lubec: "A Novel Heterocyclic Compound CE-104 Enhances Spatial Working Memory in the Radial Arm Maze in Rats and Modulates the Dopaminergic System." in: Frontiers in behavioral neuroscience, Vol. 10, pp. 20, (2016) (PubMed).

Karabacak, Sase, Aher, Sase, Saroja, Cicvaric, Höger, Berger, Bakulev, Sitte, Leban, Monje, Lubec: "The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze." in: Frontiers in behavioral neuroscience, Vol. 9, pp. 215, (2015) (PubMed).

Salamone, Zappettini, Grilli, Olivero, Agostinho, Tomé, Chen, Pittaluga, Cunha, Marchi: "Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens." in: Neuropharmacology, Vol. 79, pp. 488-97, (2014) (PubMed).

Synonyms and alternative names related to SLC6A3

solute carrier family 6 member 3 (SLC6A3), solute carrier family 6 (neurotransmitter transporter), member 3 (slc6a3), Sodium-dependent dopamine transporter (dat-1), solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (Slc6a3), solute carrier family 6 member 3 (Slc6a3), DAT, Dat1, DAT1, PKDYS, SLC6A3

Protein level used designations for SLC6A3

  • dopamine transporter variant II
  • sodium-dependent dopamine transporter
  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • sodium-dependent dopamine transporter-like
  • DA transporter
  • dopamine transporter 1
  • solute carrier family 6 member 3
  • DAT
  • solute carrier family 6, member 3
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