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SLC26A5 产品

(Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

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This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009].

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Featured SLC26A5 Categories

SLC26A5 抗体

High quality antibodies with extensive validation data.

SLC26A5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC26A5 抗体

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Cat. No. ABIN531720
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Recommended SLC26A5 蛋白

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Cat. No. ABIN7424863
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Latest Publications for our SLC26A5 Products

Dallos, Wu, Cheatham, Gao, Zheng, Anderson, Jia, Wang, Cheng, Sengupta, He, Zuo: "Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification." in: Neuron, Vol. 58, Issue 3, pp. 333-9, (2008) (PubMed).

Synonyms and alternative names related to SLC26A5

solute carrier family 26 (anion exchanger), member 5 (slc26a5), solute carrier family 26 member 5 (SLC26A5), solute carrier family 26 member 5 (slc26a5), solute carrier family 26 member 5 (Slc26a5), solute carrier family 26, member 5 (Slc26a5), DFNB61, fb73d12, fb74g12, pres, PRES, Pres, prestin, wu:fb73d12, wu:fb74g12

Protein level used designations for SLC26A5

  • prestin
  • zprestin
  • solute carrier family 26, member 5 (prestin)
  • prestin-like
  • prestin (motor protein)
  • solute carrier family 26 member 5
  • outer hair cell motor protein
  • solute carrier family 26, member 5 (prestin) isoform 1
  • solute carrier family 26, member 5 (prestin) isoform 2
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