SLC22A12 产品
(Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))
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The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
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Featured SLC22A12 Categories
SLC22A12 抗体
High quality antibodies with extensive validation data.
SLC22A12 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SLC22A12 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC22A12 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (3)
Cat. No.
ABIN530376
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7192423
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN1682756
Quantity
100 μg
Datasheet
Datasheet
Recommended SLC22A12 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959579
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959580
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232809
Quantity
96 tests
Datasheet
Datasheet
Recommended SLC22A12 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320195
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320194
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406998
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SLC22A12 Products
: "Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).: "Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout." in: Molecular biology and evolution, Vol. 33, Issue 9, pp. 2193-200, (2016) (PubMed).
: "OIT3 deficiency impairs uric acid reabsorption in renal tubule." in: FEBS letters, Vol. 586, Issue 6, pp. 760-5, (2012) (PubMed).
: "Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake." in: Metabolism: clinical and experimental, Vol. 60, Issue 9, pp. 1259-70, (2011) (PubMed).
: "The SLC22 drug transporter family." in: Pflügers Archiv : European journal of physiology, Vol. 447, Issue 5, pp. 666-76, (2004) (PubMed).
: "[Molecular biology of urate transporter]." in: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 76, Issue 2, pp. 101-10, (2004) (PubMed).
: "The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45942-50, (2004) (PubMed).
: "Two male siblings with hereditary renal hypouricemia and exercise-induced ARF." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 42, Issue 6, pp. 1287-92, (2003) (PubMed).
: "Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion." in: Journal of the American Society of Nephrology : JASN, Vol. 15, Issue 1, pp. 164-73, (2003) (PubMed).
Synonyms and alternative names related to SLC22A12
solute carrier family 22 (organic anion/cation transporter), member 12 (Slc22a12), solute carrier family 22 member 12 (SLC22A12), solute carrier family 22 member 12 (Slc22a12), AI987855, OAT4L, Rst, RST, Slc22al2, URAT1Protein level used designations for SLC22A12
- renal-specific transporter
- solute carrier family 22 (organic cation transporter)-like 2
- solute carrier family 22 member 12
- urate anion exchanger 1
- organic anion transporter 4-like protein
- solute carrier family 22 (organic anion/cation transporter), member 12
- urate transporter 1
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