SLC11A2 产品
(Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))
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This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010].
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Featured SLC11A2 Categories
SLC11A2 抗体
High quality antibodies with extensive validation data.
SLC11A2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SLC11A2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC11A2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human, Mouse, Rat
Application
ELISA, WB, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (2)
- (3)
Cat. No.
ABIN701065
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (4)
- (3)
Cat. No.
ABIN562043
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7161093
Quantity
100 μg
Datasheet
Datasheet
Recommended SLC11A2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959559
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970292
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970293
Quantity
96 tests
Datasheet
Datasheet
Recommended SLC11A2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320123
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406986
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406983
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SLC11A2 Products
: "Effect of Inflammatory Mediators Lipopolysaccharide and Lipoteichoic Acid on Iron Metabolism of Differentiated SH-SY5Y Cells Alters in the Presence of BV-2 Microglia." in: International journal of molecular sciences, Vol. 20, Issue 1, (2019) (PubMed).: "Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD." in: Molecular and cellular neurosciences, Vol. 92, pp. 164-176, (2019) (PubMed).
: "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." in: Journal of animal science, Vol. 95, Issue 4, pp. 1587-1597, (2017) (PubMed).
: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).
: "Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2." in: Biochemical pharmacology, Vol. 96, Issue 3, pp. 216-24, (2015) (PubMed).
: "Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra." in: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 900-908, (2014) (PubMed).
: "Proposing a Caco-2/HepG2 cell model for in vitro iron absorption studies." in: The Journal of nutritional biochemistry, Vol. 25, Issue 7, pp. 710-5, (2014) (PubMed).
: "The influence of combined magnesium and vanadate administration on the level of some elements in selected rat organs: V-Mg interactions and the role of iron-essential protein (DMT-1) in the mechanism ..." in: Metallomics : integrated biometal science, Vol. 6, Issue 4, pp. 907-20, (2014) (PubMed).
: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." in: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, (2011) (PubMed).
: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).
Synonyms and alternative names related to SLC11A2
solute carrier family 11 member 2 (SLC11A2), solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2), solute carrier family 11 member 2 (Slc11a2), NRAMP metal ion transporter 2 (NRAMP2), manganese transport protein (NRAMP2), metal transporter Nramp2 (LOC9327403), solute carrier family 11 member 2 (slc11a2), solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 (slc11a2), ATNRAMP2, cb426, DCT1, dct1, DMT1, Dmt1, dmt1, F8G22.4, F8G22_4, fa07b10, mk, NRAMP2, Nramp2, nramp2, NRAMP metal ion transporter 2, SLC11A2, van, wu:fa07b10, zgc:136699Protein level used designations for SLC11A2
- DMT-1
- NRAMP 2
- divalent cation transporter 1
- natural resistance-associated macrophage protein 2
- solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
- divalent metal transporter 1
- microcytic anemia, viable anaemia
- Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)
- manganese transport protein
- NRAMP2
- cdy
- chardonnay
- nramp
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