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SKP2 蛋白

(S-Phase Kinase-Associated Protein 2 (SKP2))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class\; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011].
SKP2 Protein (AA 1-424) (GST tag) SKP2 Protein (AA 1-424) (GST tag) SKP2 Protein (AA 1-424) (GST tag) (ABIN1320091)

SKP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SKP2 Protein (AA 176-285) (GST tag) SKP2 Protein (AA 176-285) (GST tag) SKP2 Protein (AA 176-285) (GST tag) (ABIN1320093)

SKP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SKP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) SKP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) SKP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2732125)

SKP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

SKP2 蛋白 by Origin

Find SKP2 蛋白 for a variety of species such as anti-Human SKP2, anti-Mouse SKP2. The species listed below are among those available. Click on a link to go to the corresponding products.

SKP2 蛋白 by Source

Here you will find SKP2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SKP2 蛋白 by 蛋白类型

Here you can find SKP2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

SKP2 蛋白 by 应用范围

Find SKP2 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SKP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320091
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320093
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732125
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413499
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095574
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120254
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711247
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1067220
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SKP2 蛋白

Wen, Wang, Yang: "Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3917-24, (2016) (PubMed).

Aliases for SKP2 蛋白

S-phase kinase-associated protein 2 (p45) (Skp2) 蛋白
S-phase kinase associated protein 2 (SKP2) 蛋白
S-phase kinase associated protein 2 (Skp2) 蛋白
FBL1 蛋白
FBXL1 蛋白
FLB1 蛋白
p45 蛋白
RGD1562456 蛋白
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