SKAP1 产品
(Src Kinase Associated phosphoprotein 1 (SKAP1))
Categories
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008].
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Featured SKAP1 Categories
Recommended SKAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
Cat. No.
ABIN563722
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN563721
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856083
Quantity
100 μL
Datasheet
Datasheet
Recommended SKAP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320072
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419238
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419241
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SKAP1 Products
: "Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome." in: Blood, Vol. 113, Issue 1, pp. 127-36, (2009) (PubMed).: "SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription." in: Molecular and cellular biology, Vol. 22, Issue 8, pp. 2673-86, (2002) (PubMed).
: "SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40420-7, (2002) (PubMed).
: "FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 15, pp. 8779-84, (1998) (PubMed).
: "SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55." in: FEBS letters, Vol. 435, Issue 1, pp. 55-60, (1998) (PubMed).
: "Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes." in: The Journal of biological chemistry, Vol. 272, Issue 26, pp. 16077-80, (1997) (PubMed).
Synonyms and alternative names related to SKAP1
src family associated phosphoprotein 1 (Skap1), src kinase associated phosphoprotein 1 (SKAP1), src kinase associated phosphoprotein 1 (Skap1), 1700091G21Rik, Scap1, SCAP1, Skap-55, SKAP55, Skap55Protein level used designations for SKAP1
- ortholog of human src family associated phosphoprotein 1 SCAP1
- src family-associated phosphoprotein 1
- src kinase-associated phosphoprotein 1
- SKAP-55
- pp55
- src family associated phosphoprotein 1
- src kinase-associated phosphoprotein of 55 kDa
- SKAP55 adapter protein
- SKAP55 adaptor protein
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