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Sjogren Syndrome Antigen B 产品

(Sjogren Syndrome Antigen B (SSB))
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. [provided by RefSeq, Nov 2011].

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Featured Sjogren Syndrome Antigen B Categories

Sjogren Syndrome Antigen B 抗体

High quality antibodies with extensive validation data.

Sjogren Syndrome Antigen B ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Sjogren Syndrome Antigen B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Sjogren Syndrome Antigen B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human
Application WB, IHC, IF, IHC (p), IP, FACS
Validations
  • (10)
Cat. No. ABIN1501143
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey
Application WB, IHC, IF, IHC (p), IP
Validations
  • (16)
Cat. No. ABIN1501146
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN3015265
Quantity 100 μL
Datasheet Datasheet

Recommended Sjogren Syndrome Antigen B ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970420
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959703
Quantity 96 tests
Datasheet Datasheet
Reactivity
Analytical Method Semi-Quantitative Competition ELISA
Validations
Cat. No. ABIN996873
Quantity 96 tests
Datasheet Datasheet

Recommended Sjogren Syndrome Antigen B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity E. coli
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (3)
Cat. No. ABIN2452175
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125112
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321383
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Sjogren Syndrome Antigen B Products

Kyriakidis, Kapsogeorgou, Gourzi, Konsta, Baltatzis, Tzioufas: "Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway." in: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 548-60, (2014) (PubMed).

Muniz, Egloff, Kiss: "RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP." in: Nucleic acids research, Vol. 41, Issue 8, pp. 4686-98, (2013) (PubMed).

Tang, Zhang, Huang, Heise, Zhang, Liu: "Phosphorylation of human La protein at Ser 366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro." in: Journal of viral hepatitis, Vol. 20, Issue 1, pp. 24-33, (2012) (PubMed).

Wang, Liu, An, Diao, Xu, He, Sun, Wei, Li: "Regulation of hepatitis C virus translation initiation by iron: role of eIF3 and La protein." in: Virus research, Vol. 167, Issue 2, pp. 302-9, (2012) (PubMed).

Nitta, Tam, Kim, Fan: "The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag." in: mBio, Vol. 2, Issue 1, pp. e00341-10, (2011) (PubMed).

Brenet, Socci, Sonenberg, Holland: "Akt phosphorylation of La regulates specific mRNA translation in glial progenitors." in: Oncogene, Vol. 28, Issue 1, pp. 128-39, (2009) (PubMed).

Bitko, Musiyenko, Bayfield, Maraia, Barik: "Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms." in: Journal of virology, Vol. 82, Issue 16, pp. 7977-87, (2008) (PubMed).

Kotik-Kogan, Valentine, Sanfelice, Conte, Curry: "Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein." in: Structure (London, England : 1993), Vol. 16, Issue 6, pp. 852-62, (2008) (PubMed).

Teplova, Yuan, Phan, Malinina, Ilin, Teplov, Patel: "Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen." in: Molecular cell, Vol. 21, Issue 1, pp. 75-85, (2006) (PubMed).

Goodier, Fan, Maraia: "A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5823-32, (1997) (PubMed).

Synonyms and alternative names related to Sjogren Syndrome Antigen B

Sjogren syndrome antigen B (SSB), Sjogren syndrome antigen B L homeolog (ssb.L), single stranded DNA binding protein 1 (SSBP1), Sjogren syndrome antigen B (Ssb), Sjogren syndrome antigen B S homeolog (ssb.S), Sjogren syndrome antigen B (autoantigen La) (ssb), La, laa-a, lab1, LARP3, larp3, Mt-SSB, MtSSB, SS-B, ssb, ssb-a, ssb-b, Ssbp1, wu:fb17f11, zgc:55588

Protein level used designations for Sjogren Syndrome Antigen B

  • La ribonucleoprotein domain family, member 3
  • SS-B
  • SS-B/La protein
  • autoantigen La
  • la autoantigen
  • lupus La antigen
  • lupus La protein
  • sjoegren syndrome type B antigen
  • la autoantigen homolog
  • la ribonucleoprotein
  • lupus La protein homolog
  • la autoantigen homolog B
  • la ribonucleoprotein B
  • lupus La protein homolog B
  • single-stranded DNA binding
  • single-stranded DNA-binding protein, mitochondrial
  • La protein
  • Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog)
  • mRNA for autoantigen
  • La autoantigen homolog A
  • La protein form A
  • La ribonucleoprotein A
  • Sjogren syndrome antigen B (autoantigen La)
  • la autoantigen homolog A
  • la ribonucleoprotein A
  • lupus La protein homolog A
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