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SIRT6 抗体

(Sirtuin 6 (SIRT6))
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010].
SIRT6 抗体  (AA 1-334) SIRT6 抗体  (AA 1-334) SIRT6 抗体 (AA 1-334) (ABIN7437191)

SIRT6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

SIRT6 抗体  (AA 141-250) SIRT6 抗体  (AA 141-250) SIRT6 抗体 (AA 141-250) (ABIN5542442)

SIRT6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2G1H1 unconjugated

SIRT6 抗体 SIRT6 抗体 SIRT6 抗体 (ABIN6241508)

SIRT6 适用: 人, 小鼠, 大鼠, 猴 WB, IP, IF 宿主: 小鼠 Monoclonal 6C9-D10-D3 unconjugated

SIRT6 抗体 by 适用

Find SIRT6 抗体 for a variety of species such as anti-Human SIRT6, anti-Mouse SIRT6, anti-Rat SIRT6. The species listed below are among those available. Click on a link to go to the corresponding products.

SIRT6 抗体 by 应用范围

Find SIRT6 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SIRT6 抗体 by 抗体来源

Find SIRT6 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SIRT6 抗体 by 抗原表位

Find SIRT6 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SIRT6 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SIRT6 抗体. Click on a link to go to the corresponding products.

SIRT6 抗体 by 克隆

Find SIRT6 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SIRT6 抗体 by 标记

Find SIRT6 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SIRT6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7437191
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IP, IF
Validations
  • (3)
Cat. No. ABIN6241508
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Rat
Application WB, IP, ChIP
Validations
  • (2)
  • (3)
Cat. No. ABIN2779624
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN2779625
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7435934
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN526804
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Dog, Hamster, Human, Monkey, Mouse, Pig
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN768730
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6972723
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6746986
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN6147800
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN3043435
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
  • (2)
Cat. No. ABIN390181
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3032596
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3032598
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our SIRT6 抗体

Zhang, Bai, Ren, Sun, Si: "Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70." in: Molecular immunology, Vol. 101, pp. 312-318, (2019) (PubMed).

Xia, Hua, Juan, Zhong, Tao, Fang, Lin, Rui, Yong: "SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression." in: Frontiers in pharmacology, Vol. 9, pp. 194, (2018) (PubMed).

Li, Shi, Yang, Yan, Zhang, Yang, He, Li, Yi, Sun, Liang, Cheng, Shi, Shang, Yu: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." in: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).

Zhu, Yan, Shao, Tian, Zhou: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).

Tao, Ren, Tang, Ran, Zhou, Liu, Huang, Chen: "Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 485, Issue 4, pp. 713-719, (2017) (PubMed).

Ran, Chen, Zhang, Tao, Ren, Zhou, Tang, Chen, Chen, Li, Huang, Chen: "SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 13, pp. 3372-82, (2016) (PubMed).

Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

Azuma, Yokobori, Mogi, Altan, Yajima, Kosaka, Onozato, Yamaki, Asao, Nishiyama, Kuwano: "SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer." in: Journal of surgical oncology, Vol. 112, Issue 2, pp. 231-7, (2015) (PubMed).

Tran, Schulkin, Ligon, Greenwood-Van Meerveld: "Epigenetic modulation of chronic anxiety and pain by histone deacetylation." in: Molecular psychiatry, Vol. 20, Issue 10, pp. 1219-31, (2015) (PubMed).

Cardinale, de Stefano, Mollinari, Racaniello, Garaci, Merlo: "Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response." in: Neurochemical research, Vol. 40, Issue 1, pp. 59-69, (2015) (PubMed).

Aliases for SIRT6 抗体

sirtuin 6 (Sirt6) 抗体
sirtuin 6 (SIRT6) 抗体
sirtuin 6 S homeolog (sirt6.S) 抗体
sirtuin 6 (sirt6) 抗体
2810449N18Rik 抗体
AI043036 抗体
Sir2l6 抗体
SIR2L6 抗体
zgc:86729 抗体
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