SIGLEC8 抗体
(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM\\\\; MIM 603492) that mediates an association with SLAM-associated protein (SAP\\\\; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010].
recommended
recommended
recommended
SIGLEC8 抗体 by Grade
Find SIGLEC8 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 适用
Find SIGLEC8 抗体 for a variety of species such as anti-Human SIGLEC8, anti-Mouse SIGLEC8, anti-Rat SIGLEC8. The species listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 应用范围
Find SIGLEC8 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 抗体来源
Find SIGLEC8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SIGLEC8 抗体. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 克隆
Find SIGLEC8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC8 抗体 by 标记
Find SIGLEC8 抗体 with a specific conjugate such as Biotin, PE, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular SIGLEC8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN565353
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN525889
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7186224
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7426355
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7255347
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN308467
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IP, FACS
Validations
- (1)
Cat. No.
ABIN7013899
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (1)
Cat. No.
ABIN7506011
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6147766
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN1870885
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN5534688
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN5534687
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2998632
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN357149
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN7467436
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our SIGLEC8 抗体
: "Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis." in: JCI insight, Vol. 4, Issue 19, (2019) (PubMed).: "Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 2, pp. 499-505.e1, (2008) (PubMed).
: "Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies." in: The Journal of allergy and clinical immunology, Vol. 119, Issue 4, pp. 1005-11, (2007) (PubMed).
: "Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis." in: Blood, Vol. 101, Issue 12, pp. 5014-20, (2003) (PubMed).
: "Molecular characterization of a Siglec8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the Siglec8 gene." in: Biochemical and biophysical research communications, Vol. 278, Issue 3, pp. 775-81, (2000) (PubMed).
: "Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily." in: The Journal of biological chemistry, Vol. 275, Issue 2, pp. 861-6, (2000) (PubMed).
: "Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils." in: The Journal of allergy and clinical immunology, Vol. 105, Issue 6 Pt 1, pp. 1093-100, (2000) (PubMed).
Aliases for SIGLEC8 抗体
sialic acid binding Ig like lectin 8 (SIGLEC8) 抗体sialic acid-binding Ig-like lectin 8 (LOC506364) 抗体
SAF2 抗体
SIGLEC-8 抗体
SIGLEC8 抗体
SIGLEC8L 抗体
您还需要查找其他产品吗？
- SIGLEC7 抗体
- SIGLEC6 抗体
- SIGLEC5 抗体
- SIGLEC15 抗体
- SIGLEC14 抗体
- SIGLEC12 抗体
- SIGLEC11 抗体
- SIGLEC10 抗体
- SIGIRR 抗体
- SIDT2 抗体
- SIDT1 抗体
- Sideroflexin 4 抗体
- Sialoadhesin/CD169 抗体
- Sialidase 4 抗体
- SIAH2 抗体
- SIAH1 抗体
- SIAE 抗体
- Shugoshin 抗体
- SHROOM3 抗体
- SHROOM2 抗体
- SIGLEC9 抗体
- Siglece 抗体
- SIGMAR1 抗体
- Signal Recognition Particle 54A 抗体
- Signal Transducing Adaptor Family Member 2 抗体
- SIK1 抗体
- SIK2 抗体
- SIKE1 抗体
- SIL1 抗体
- SIM1 抗体
- SIM2 抗体
- SIN3A 抗体
- Sin3A-Associated Protein, 130kDa 抗体
- SIN3B 抗体
- Sine Oculis-Related Homeobox 3 抗体
- Single-Stranded DNA Binding Protein 1 抗体
- SIP1 抗体
- SIPA1 抗体
- SIPA1L1 抗体
- SIRPA 抗体
You are here:
