SIGLEC7 抗体
(Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
recommended
SIGLEC7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
recommended
recommended
SIGLEC7 抗体 by 适用
Find SIGLEC7 抗体 for a variety of species such as anti-Human SIGLEC7, anti-Mouse SIGLEC7, anti-Monkey SIGLEC7. The species listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC7 抗体 by 抗体来源
Find SIGLEC7 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC7 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SIGLEC7 抗体. Click on a link to go to the corresponding products.
SIGLEC7 抗体 by 克隆
Find SIGLEC7 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC7 抗体 by 标记
Find SIGLEC7 抗体 with a specific conjugate such as FITC, Biotin, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
SIGLEC7 抗体 by Fragment
Find SIGLEC7 抗体 with a specific Fragment. The Fragment listed below are among those available. Click on a link to go to the corresponding products.
Popular SIGLEC7 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7169566
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7438064
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (3)
Cat. No.
ABIN2749127
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), ICC, IF
Validations
- (3)
Cat. No.
ABIN2856478
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7427762
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN525812
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (2)
Cat. No.
ABIN2749061
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1175022
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN388428
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032556
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032557
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN5587916
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6738299
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6738298
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (1)
Cat. No.
ABIN7490814
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SIGLEC7 抗体
: "Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes." in: Scientific reports, Vol. 7, pp. 45319, (2017) (PubMed).: "Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides." in: PLoS biology, Vol. 10, Issue 12, pp. e1001448, (2012) (PubMed).
: "Engagement of Siglec-7 receptor induces a pro-inflammatory response selectively in monocytes." in: PLoS ONE, Vol. 7, Issue 9, pp. e45821, (2012) (PubMed).
: "Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids." in: PLoS ONE, Vol. 6, Issue 9, pp. e24559, (2011) (PubMed).
: "Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates." in: Cellular immunology, Vol. 250, Issue 1-2, pp. 91-104, (2008) (PubMed).
: "Sialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharides." in: Infection and immunity, Vol. 74, Issue 7, pp. 4133-41, (2006) (PubMed).
: "High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family." in: The Journal of biological chemistry, Vol. 278, Issue 5, pp. 3372-7, (2003) (PubMed).
: "Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms." in: European journal of immunology, Vol. 33, Issue 6, pp. 1642-8, (2003) (PubMed).
Aliases for SIGLEC7 抗体
sialic acid-binding Ig-like lectin 7 (LOC468976) 抗体sialic acid binding Ig like lectin 7 (SIGLEC7) 抗体
AIRM1 抗体
CD328 抗体
CDw328 抗体
D-siglec 抗体
p75 抗体
p75/AIRM1 抗体
QA79 抗体
SIGLEC-7 抗体
SIGLEC7 抗体
SIGLEC19P 抗体
SIGLECP2 抗体
您还需要查找其他产品吗？
- SIGLEC6 抗体
- SIGLEC5 抗体
- SIGLEC15 抗体
- SIGLEC14 抗体
- SIGLEC12 抗体
- SIGLEC11 抗体
- SIGLEC10 抗体
- SIGIRR 抗体
- SIDT2 抗体
- SIDT1 抗体
- Sideroflexin 4 抗体
- Sialoadhesin/CD169 抗体
- Sialidase 4 抗体
- SIAH2 抗体
- SIAH1 抗体
- SIAE 抗体
- Shugoshin 抗体
- SHROOM3 抗体
- SHROOM2 抗体
- SHROOM1 抗体
- SIGLEC8 抗体
- SIGLEC9 抗体
- Siglece 抗体
- SIGMAR1 抗体
- Signal Recognition Particle 54A 抗体
- Signal Transducing Adaptor Family Member 2 抗体
- SIK1 抗体
- SIK2 抗体
- SIKE1 抗体
- SIL1 抗体
- SIM1 抗体
- SIM2 抗体
- SIN3A 抗体
- Sin3A-Associated Protein, 130kDa 抗体
- SIN3B 抗体
- Sine Oculis-Related Homeobox 3 抗体
- Single-Stranded DNA Binding Protein 1 抗体
- SIP1 抗体
- SIPA1 抗体
- SIPA1L1 抗体
You are here:
