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SIGLEC12 抗体

(Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
SIGLEC12 抗体  (AA 503-595) SIGLEC12 抗体  (AA 503-595) SIGLEC12 抗体 (AA 503-595) (ABIN529939)

SIGLEC12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D1 unconjugated

SIGLEC12 抗体  (AA 27-141) SIGLEC12 抗体  (AA 27-141) SIGLEC12 抗体 (AA 27-141) (ABIN7437041)

SIGLEC12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

SIGLEC12 抗体  (AA 20-210) SIGLEC12 抗体  (AA 20-210) SIGLEC12 抗体 (AA 20-210) (ABIN7169557)

SIGLEC12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

SIGLEC12 抗体 by 适用

Find SIGLEC12 抗体 for a variety of species such as anti-Human SIGLEC12, anti-Mouse SIGLEC12, anti-Cow SIGLEC12. The species listed below are among those available. Click on a link to go to the corresponding products.

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SIGLEC12 抗体 by 抗原表位

Find SIGLEC12 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SIGLEC12 抗体 by 克隆形成能力

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SIGLEC12 抗体 by 克隆

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SIGLEC12 抗体 by 标记

Find SIGLEC12 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SIGLEC12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN529939
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7437041
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN7169557
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7264571
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN529938
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6738691
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6738692
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6738684
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6147759
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN634721
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1174410
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5537532
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
Cat. No. ABIN7466644
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2571222
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
Cat. No. ABIN2571223
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SIGLEC12 抗体

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Yu, Lai, Maoui, Banville, Shen: "Identification and characterization of S2V, a novel putative siglec that contains two V set Ig-like domains and recruits protein-tyrosine phosphatases SHPs." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 23816-24, (2001) (PubMed).

Angata, Varki, Varki: "A second uniquely human mutation affecting sialic acid biology." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40282-7, (2001) (PubMed).

Aliases for SIGLEC12 抗体

sialic acid binding Ig like lectin 12 (gene/pseudogene) (SIGLEC12) 抗体
sialic acid binding Ig like lectin 12 (SIGLEC12) 抗体
sialic acid binding Ig-like lectin 12 (SIGLEC12) 抗体
S2V 抗体
Siglec-XII 抗体
SIGLECL1 抗体
SLG 抗体
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