SIAH2 产品
(Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
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This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008].
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Featured SIAH2 Categories
SIAH2 抗体
High quality antibodies with extensive validation data.
SIAH2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SIAH2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIAH2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6265080
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7151218
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN652059
Quantity
400 μL
Datasheet
Datasheet
Recommended SIAH2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1131322
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1131323
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1131324
Quantity
96 tests
Datasheet
Datasheet
Recommended SIAH2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319979
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319977
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095363
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SIAH2 Products
: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." in: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).: "The E3 ubiquitin ligase Sina regulates the assembly and disassembly of the synaptonemal complex in Drosophila females." in: PLoS genetics, Vol. 15, Issue 5, pp. e1008161, (2019) (PubMed).
: "DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor." in: Oncogene, Vol. 37, Issue 5, pp. 638-650, (2018) (PubMed).
: "Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways." in: Nature communications, Vol. 7, pp. 11123, (2016) (PubMed).
: "SIAH2 protein expression in breast cancer is inversely related with ER status and outcome to tamoxifen therapy." in: American journal of cancer research, Vol. 6, Issue 2, pp. 270-84, (2016) (PubMed).
: "SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer." in: EBioMedicine, Vol. 11, pp. 183-198, (2016) (PubMed).
: "Increased expression of PHD3 represses the HIF-1 signaling pathway and contributes to poor neovascularization in pancreatic ductal adenocarcinoma." in: Journal of gastroenterology, Vol. 50, Issue 9, pp. 975-83, (2015) (PubMed).
: "Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer." in: British journal of cancer, Vol. 112, Issue 3, pp. 514-22, (2015) (PubMed).
: "The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143376, (2015) (PubMed).
: "Loss of Siah2 does not impact angiogenic potential of murine endothelial cells." in: Microvascular research, Vol. 102, pp. 38-45, (2015) (PubMed).
Synonyms and alternative names related to SIAH2
siah E3 ubiquitin protein ligase 2 (SIAH2), siah E3 ubiquitin protein ligase 2 L homeolog (siah2.L), seven in absentia 2 (Siah2), siah E3 ubiquitin protein ligase 2 (Siah2), AA415433, hSiah2, siah2-A, Sinh2, Xsiah-2, xsiah2Protein level used designations for SIAH2
- E3 ubiquitin-protein ligase SIAH2
- seven in absentia homolog 2
- siah-2
- seven in absentia-like protein
- E3 ubiquitin-protein ligase siah2
- mSiah2
- seven in absentia 2
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