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SHMT2 产品

(serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2))

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This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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Featured SHMT2 Categories

SHMT2 抗体

High quality antibodies with extensive validation data.

SHMT2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SHMT2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7443701
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7255944
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (6)
Cat. No. ABIN3021747
Quantity 100 μL
Datasheet Datasheet

Recommended SHMT2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232362
Quantity 96 tests
Datasheet Datasheet

Recommended SHMT2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125035
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319956
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319955
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our SHMT2 Products

Kim, Fiske, Birsoy, Freinkman, Kami, Possemato, Chudnovsky, Pacold, Chen, Cantor, Shelton, Gui, Kwon, Ramkissoon, Ligon, Kang, Snuderl, Vander Heiden, Sabatini: "SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance." in: Nature, Vol. 520, Issue 7547, pp. 363-7, (2015) (PubMed).

Kjellin, Johansson, Höög, Lehtiö, Jakobsson, Kjellman: "Differentially expressed proteins in malignant and benign adrenocortical tumors." in: PLoS ONE, Vol. 9, Issue 2, pp. e87951, (2014) (PubMed).

Synonyms and alternative names related to SHMT2

serine hydroxymethyltransferase 2 (SHMT2), serine hydroxymethyltransferase 2 (mitochondrial) (Chro.80302), serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), serine hydroxymethyltransferase 2 (Shmt2), serine hydroxymethyltransferase 2 (mitochondrial) (shmt2), serine hydroxymethyltransferase 2 (mitochondrial) L homeolog (shmt2.L), serine hydroxymethyltransferase, mitochondrial-like (SHMT), 2700043D08Rik, AA408223, AA986903, GLYA, SHMT

Protein level used designations for SHMT2

  • GLY A+
  • glycine auxotroph A, human complement for hamster
  • glycine hydroxymethyltransferase
  • serine aldolase
  • serine hydroxymethylase
  • serine hydroxymethyltransferase, mitochondrial
  • serine methylase
  • threonine aldolase
  • SHMT
  • serine hydroxymethyltransferase 2 (mitochondrial)
  • mitochondrial serine hydroxymethyltransferase
  • Glycine hydroxymethyltransferase
  • Serine methylase
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