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SHANK1 产品

(SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

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Featured SHANK1 Categories

SHANK1 抗体

High quality antibodies with extensive validation data.

SHANK1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended SHANK1 抗体

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Cat. No. ABIN2483711
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Recommended SHANK1 ELISA试剂盒

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Latest Publications for our SHANK1 Products

Wolstenholme, Drobná, Henriksen, Goldsby, Stevenson, Irvin, Flaws, Rissman: "Transgenerational Bisphenol A Causes Deficits in Social Recognition and Alters Postsynaptic Density Genes in Mice." in: Endocrinology, Vol. 160, Issue 8, pp. 1854-1867, (2019) (PubMed).

Kerrisk Campbell, Sheng: "USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 23, pp. 5289-5301, (2018) (PubMed).

Heise, Schroeder, Schoen, Halbedl, Reim, Woelfle, Kreutz, Schmeisser, Boeckers: "Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus." in: Frontiers in cellular neuroscience, Vol. 10, pp. 106, (2016) (PubMed).

Farley, Swulius, Waxham: "Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities." in: Neuroscience, Vol. 304, pp. 286-301, (2015) (PubMed).

Braude, Vijayakumar, Baumgarner, Laurine, Jones, Jones, Pyott: "Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear." in: Hearing research, Vol. 321, pp. 52-64, (2015) (PubMed).

Hagmeyer, Mangus, Boeckers, Grabrucker: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).

Williams, DeSpenza, Li, Gulledge, Luikart: "Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 943-59, (2015) (PubMed).

Zhang, Zheng, Wan, Shao, Liu, Zhang, Zhang: "The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 192, pp. 317-24, (2014) (PubMed).

Catarino, Ribeiro, Santos, Carvalho: "Regulation of synapse composition by protein acetylation: the role of acetylated cortactin." in: Journal of cell science, Vol. 126, Issue Pt 1, pp. 149-62, (2013) (PubMed).

Han, Holder, Schaaf, Lu, Chen, Kang, Tang, Wu, Hao, Cheung, Yu, Sun, Breman, Patel, Lu, Zoghbi: "SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties." in: Nature, Vol. 503, Issue 7474, pp. 72-7, (2013) (PubMed).

Synonyms and alternative names related to SHANK1

SH3 and multiple ankyrin repeat domains 1 (SHANK1), SH3 and multiple ankyrin repeat domains 1 (Shank1), Shank1a, SPANK-1, Spank1, SSTRIP, Sstrip, synamon

Protein level used designations for SHANK1

  • SH3 and multiple ankyrin repeat domains protein 1
  • SSTR-interacting protein
  • somatostatin receptor-interacting protein
  • GKAP/SAPAP interacting protein
  • GKAP/SAPAP-interacting protein
  • SAPAP-interacting protein synamon
  • SH3/ankyrin domain gene 1
  • SPANK-1
  • synamon
  • SH3 and multiple ankyrin repeat domains 1
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