SH3BP2 产品
(SH3-Domain Binding Protein 2 (SH3BP2))
Categories
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured SH3BP2 Categories
SH3BP2 抗体
High quality antibodies with extensive validation data.
SH3BP2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SH3BP2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SH3BP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
Cat. No.
ABIN562859
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6744458
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7169491
Quantity
100 μg
Datasheet
Datasheet
Recommended SH3BP2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970198
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959458
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658774
Quantity
96 tests
Datasheet
Datasheet
Recommended SH3BP2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319884
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408924
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3088254
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SH3BP2 Products
: "Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2." in: The Journal of clinical investigation, Vol. 126, Issue 12, pp. 4482-4496, (2016) (PubMed).: "The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7146-53, (2003) (PubMed).
: "Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism." in: American journal of medical genetics. Part A, Vol. 121A, Issue 1, pp. 37-40, (2003) (PubMed).
: "A missense mutation in the SH3BP2 gene on chromosome 4p16.3 found in a case of nonfamilial cherubism." in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, Vol. 40, Issue 6, pp. 632-8, (2003) (PubMed).
Synonyms and alternative names related to SH3BP2
SH3 domain binding protein 2 (SH3BP2), SH3-domain binding protein 2 (Sh3bp2), 3BP-2, 3BP2, CRBM, CRPM, SH3BP2Protein level used designations for SH3BP2
- SH3-domain binding protein 2
- SH3 domain-binding protein 2
- Abl-SH3 binding protein 2
- TNFAIP3 interacting protein 2
- 3BP-2
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