SH2B2 产品
(SH2B Adaptor Protein 2 (SH2B2))
Categories
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009].
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Featured SH2B2 Categories
Recommended SH2B2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7192349
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IF, ICC
Validations
- (2)
Cat. No.
ABIN6256908
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN7185885
Quantity
100 μg
Datasheet
Datasheet
Recommended SH2B2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319859
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095479
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137272
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SH2B2 Products
: "Identification of SH2B2beta as an inhibitor for SH2B1- and SH2B2alpha-promoted Janus kinase-2 activation and insulin signaling." in: Endocrinology, Vol. 148, Issue 4, pp. 1615-21, (2007) (PubMed).: "Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 37827-32, (2005) (PubMed).
: "APS, an adaptor molecule containing PH and SH2 domains, has a negative regulatory role in B cell proliferation." in: Biochemical and biophysical research communications, Vol. 330, Issue 3, pp. 1005-13, (2005) (PubMed).
Synonyms and alternative names related to SH2B2
SH2B adaptor protein 2 (SH2B2), SH2B adaptor protein 2 (Sh2b2), APS, ApsProtein level used designations for SH2B2
- SH2 and PH domain-containing adapter protein APS
- SH2B adapter protein 2
- adapter protein with pleckstrin homology and Src homology 2 domains
- adaptor protein with pleckstrin homology and src homology 2 domains
- insulin receptor substrate 5
- SH2B adaptor protein 2
- SH2B adapter protein 2-like
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