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SGCG 产品

(Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG))

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This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008].

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Featured SGCG Categories

SGCG 抗体

High quality antibodies with extensive validation data.

SGCG 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SGCG 抗体

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Reactivity
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Datasheet
Reactivity Human
Application WB, IP
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Cat. No. ABIN520158
Quantity 100 μL
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Reactivity Human
Application WB, ELISA, IP
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  • (3)
Cat. No. ABIN520160
Quantity 100 μg
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Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
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  • (3)
Cat. No. ABIN6265040
Quantity 100 μL
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Recommended SGCG ELISA试剂盒

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Reactivity
Analytical Method
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Cat. No.
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231046
Quantity 96 tests
Datasheet Datasheet

Recommended SGCG 蛋白

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Source Wheat germ
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Cat. No. ABIN1319810
Quantity 10 μg
Datasheet Datasheet
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Cat. No. ABIN1319808
Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3099671
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Latest Publications for our SGCG Products

Chrzanowski, Vohra, Lee-McMullen, Batra, Spradlin, Morales, Forbes, Vandenborne, Barton, Walter: "Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy." in: Molecular imaging, Vol. 16, pp. 1536012117732439, (2018) (PubMed).

Rafii, Hagiwara, Mercado, Seo, Xu, Dugan, Owens, Hook, McQuillan, Young, Fallon: "Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development." in: Journal of cellular physiology, Vol. 209, Issue 2, pp. 439-47, (2006) (PubMed).

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, (2004) (PubMed).

Thompson, Chan, Hack, Brosius, Rajala, Lidov, McNally, Watkins, Kunkel: "Filamin 2 (FLN2): A muscle-specific sarcoglycan interacting protein." in: The Journal of cell biology, Vol. 148, Issue 1, pp. 115-26, (2000) (PubMed).

Piccolo, Jeanpierre, Leturcq, Dodé, Azibi, Toutain, Merlini, Jarre, Navarro, Krishnamoorthy, Tomé, Urtizberea, Beckmann, Campbell, Kaplan: "A founder mutation in the gamma-sarcoglycan gene of gypsies possibly predating their migration out of India." in: Human molecular genetics, Vol. 5, Issue 12, pp. 2019-22, (1997) (PubMed).

McNally, Passos-Bueno, Bönnemann, Vainzof, de Sá Moreira, Lidov, Othmane, Denton, Vance, Zatz, Kunkel: "Mild and severe muscular dystrophy caused by a single gamma-sarcoglycan mutation." in: American journal of human genetics, Vol. 59, Issue 5, pp. 1040-7, (1996) (PubMed).

Noguchi, McNally, Ben Othmane, Hagiwara, Mizuno, Yoshida, Yamamoto, Bönnemann, Gussoni, Denton, Kyriakides, Middleton, Hentati, Ben Hamida, Nonaka, Vance, Kunkel, Ozawa: "Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy." in: Science (New York, N.Y.), Vol. 270, Issue 5237, pp. 819-22, (1995) (PubMed).

Synonyms and alternative names related to SGCG

sarcoglycan, gamma (sgcg), sarcoglycan gamma (SGCG), sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), sarcoglycan gamma (Sgcg), sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg), sarcoglycan, gamma (Sgcg), 35DAG, 35kDa, 5430420E18Rik, A4, AI642964, DAGA4, DMDA, DMDA1, Gamma-SG, gamma-SG, LGMD2C, MAM, SCARMD2, SCG3, TYPE, zgc:100924

Protein level used designations for SGCG

  • gamma-sarcoglycan
  • 35 kDa dystrophin-associated glycoprotein
  • 35DAG
  • 35kD dystrophin-associated glycoprotein
  • gamma sarcoglycan
  • gamma-SG
  • sgcg gene for gamma-sarcoglycan
  • sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
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