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Secreted Frizzled-Related Protein 1 产品

(Secreted Frizzled-Related Protein 1 (SFRP1))
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling\; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009].

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Featured Secreted Frizzled-Related Protein 1 Categories

Secreted Frizzled-Related Protein 1 抗体

High quality antibodies with extensive validation data.

Secreted Frizzled-Related Protein 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Secreted Frizzled-Related Protein 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Secreted Frizzled-Related Protein 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7436171
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (3)
Cat. No. ABIN129592
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN674694
Quantity 100 μL
Datasheet Datasheet

Recommended Secreted Frizzled-Related Protein 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6959284
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959285
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975251
Quantity 96 tests
Datasheet Datasheet

Recommended Secreted Frizzled-Related Protein 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7275578
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319735
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398683
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Secreted Frizzled-Related Protein 1 Products

Hu, Liu, Lu, Wang, Chen, Guo, Han, Wang, Li, Liu: "sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway." in: Acta pharmacologica Sinica, Vol. 41, Issue 9, pp. 1150-1157, (2020) (PubMed).

Li, Ye, Guo, Wang, Huang, Peng: "PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 85, (2018) (PubMed).

Niu, Lin, Yuan, Chen, Yang, Chung, Lu, Tsai, Lai, Chen: "Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL." in: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 61, (2017) (PubMed).

Kim, Chang, Park, Park, Kim, Lee, Kong: "Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial." in: PLoS ONE, Vol. 12, Issue 2, pp. e0171771, (2017) (PubMed).

Kierulf-Vieira, Sandberg, Grieg, Günther, Langmoen, Vik-Mo: "Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation." in: Experimental cell research, Vol. 340, Issue 1, pp. 53-61, (2016) (PubMed).

Zang, Zhang, Gao, Huang: "Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).

Chang, Lei, Qin, Zeng, Zhang, Jin, Wang, Wang, Su: "Expression and prognostic value of SFRP1 and β-catenin in patients with glioblastoma." in: Oncology letters, Vol. 11, Issue 1, pp. 69-74, (2016) (PubMed).

Wang, Xie, Xie, Wan, Ma, Qi, Yang: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).

Zhou, Chen, Mashrah, Zhu, Liu, Yang, He, Wang, Xiang, Yao, Guo, Yang, Zhang: "Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis." in: OncoTargets and therapy, Vol. 8, pp. 2923-31, (2015) (PubMed).

Taylan, Sari, Akinci, Bilge, Kozaci, Akar, Colak, Yalcin, Gunay, Akkoc: "Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis." in: BMC musculoskeletal disorders, Vol. 13, pp. 191, (2012) (PubMed).

Synonyms and alternative names related to Secreted Frizzled-Related Protein 1

secreted frizzled related protein 1 (SFRP1), secreted frizzled-related protein 1 (Sfrp1), secreted frizzled-related protein 1 (sfrp1), secreted frizzled related protein 1 (sfrp1), Secreted frizzled-related protein 1 (sfrp1), secreted frizzled related protein 1 (Sfrp1), secreted frizzled-related protein 1a (sfrp1a), secreted frizzled-related protein 1b (sfrp1b), 2210415K03Rik, AW011917, AW107218, AW742929, CSFRP1, FRP, frp, FRP-1, frp-1, FRP1, frp1, FrzA, frzA, LOC100231868, SARP2, sarp2, sFRP-1, SFRP1, sfrp1, Srfp1a, wu:fd19b09, XfrzA

Protein level used designations for Secreted Frizzled-Related Protein 1

  • SARP-2
  • sFRP-1
  • secreted apoptosis-related protein 2
  • secreted frizzled-related sequence protein 1
  • frizzled in aorta protein
  • frzA protein
  • secreted frizzled related protein 1
  • secreted frizzled-related protein 1
  • Secreted frizzled-related protein 1
  • secreted frizzled-related protein 1a
  • secreted frizzled-related protein 1b
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