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兔 anti-人 IgM Heavy Chain Antibody

IHC (p) Monoclonal IGHM-2559R IgG kappa unconjugated
产品编号 ABIN6654259
发货至: 中国
  • 抗原
    IgM Heavy Chain
    适用
    宿主
    • 1
    克隆类型
    • 1
    单克隆
    应用范围
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified
    纯度
    Protein A affinity chromatography
    免疫原
    Recombinant heavy chain of human IgM was used as the immunogen for this recombinant IgM antibody.
    克隆位点
    IGHM-2559R
    亚型
    IgG kappa
  • 应用备注
    The optimal dilution of the recombinant IgM antibody for each application should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    限制
    仅限研究用
  • 缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the recombinant IgM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    IgM Heavy Chain
    背景
    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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