山羊 anti-人 IgA (Free & Bound), (Secretory Component) Antibody
ID, IP
Polyclonal
unconjugated
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- 抗原 See all IgA products
- IgA
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抗原表位
- Free & Bound, Secretory Component
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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应用范围
- Immunodiffusion (ID), Immunoprecipitation (IP)
- 纯化方法
- Serum
- 免疫原
- Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM. Purified free human secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Restore by adding 0.5 mLsterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2
- 注意事项
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Avoid repeated freezing and thawing.
Dilutions may be prepared by adding PBS, pH 7.2 - 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to and following reconstitution store the antibody at 2-8 °C for one month or at -28 °C for longer.
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- 抗原
- IgA
- Abstract
- IgA 产品
- 物质类
- Antibody
- 背景
- Synonyms: Human Immunoglobulin A
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