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小鼠 anti-人 Ig (Chain lambda), (Light Chain) Antibody (PE)

FACS Monoclonal Mc24-IC6 IgG1 PE
产品编号 ABIN118383
发货至: 中国
  • 抗原 See all Ig products
    Ig
    抗原表位
    • 88
    • 86
    • 68
    • 32
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Chain lambda, Light Chain
    适用
    • 108
    • 61
    • 26
    • 17
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 98
    • 73
    • 36
    • 20
    • 2
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 111
    • 95
    单克隆
    标记
    • 59
    • 29
    • 22
    • 21
    • 17
    • 16
    • 10
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    PE
    应用范围
    • 162
    • 125
    • 86
    • 67
    • 41
    • 26
    • 25
    • 14
    • 12
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Purified human IgG. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
    克隆位点
    Mc24-IC6
    亚型
    IgG1
  • 应用备注
    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL distilled water
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    RT/4 °C/-20 °C
    储存方法
    Lyophilized: Store at 2-8 °C (preferably in a desiccator). Reconstituted: Aliquot and store at -20 °C.
  • 抗原
    Ig
    别名
    Immunoglobulin (Ig 产品)
    背景
    All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5 kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L, Lambda, 0.4-4.2 mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
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