SESN1 产品
(Sestrin 1 (SESN1))
Categories
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
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Featured SESN1 Categories
SESN1 抗体
High quality antibodies with extensive validation data.
SESN1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SESN1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SESN1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (3)
Cat. No.
ABIN525920
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7270259
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7169405
Quantity
100 μg
Datasheet
Datasheet
Recommended SESN1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970187
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970186
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959448
Quantity
96 tests
Datasheet
Datasheet
Recommended SESN1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319663
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398668
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3076724
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SESN1 Products
: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).: "IGF-1 receptor antagonism inhibits autophagy." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4528-44, (2013) (PubMed).
Synonyms and alternative names related to SESN1
sestrin 1 (SESN1), sestrin 1 (sesn1), sestrin 1 (Sesn1), sestrin 1 L homeolog (sesn1.L), 1110002G11Rik, AU044290, pa26, PA26, Pa26, SESN1, sesn1-A, sest1, SEST1, Sest1, sestrin-1, XPA26, zgc:91970Protein level used designations for SESN1
- sestrin 1
- sestrin-1
- nuclear factor XPA26-T2
- p53 activated gene 26
- p53 regulated PA26 nuclear protein
- p53 regulated Pa26 nuclear protein
- p53-regulated protein PA26
- XPA26
- sestrin 1,nuclear factor XPA26-T2
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