SERPINC1 产品
(Serpin Family C Member 1 (SERPINC1))
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The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009].
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Featured SERPINC1 Categories
SERPINC1 抗体
High quality antibodies with extensive validation data.
SERPINC1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SERPINC1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SERPINC1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity
Human
Application
WB, IHC, IP, ICC
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- (7)
Cat. No.
ABIN7426502
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
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- (6)
Cat. No.
ABIN7429274
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7444019
Quantity
100 μL
Datasheet
Datasheet
Recommended SERPINC1 ELISA试剂盒
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Reactivity
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6574304
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (3)
Cat. No.
ABIN6720495
Quantity
96 tests
Datasheet
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Reactivity
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Analytical Method
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Cat. No.
ABIN6970109
Quantity
96 tests
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Recommended SERPINC1 蛋白
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Reactivity
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Escherichia coli (E. coli)
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Cat. No.
ABIN5853560
Quantity
100 μg
Datasheet
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Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319632
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505057
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SERPINC1 Products
: "iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 1, pp. 216-232, (2019) (PubMed).: "LDL extracellular vesicle coagulation protein levels change after initiation of statin therapy. Findings from the METEOR trial." in: International journal of cardiology, Vol. 271, pp. 247-253, (2019) (PubMed).
: "Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles." in: International journal of molecular sciences, Vol. 19, Issue 1, (2018) (PubMed).
: "Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family." in: Journal of proteomics, Vol. 148, pp. 139-48, (2016) (PubMed).
: "Thalidomide and multiple myeloma serum synergistically induce a hemostatic imbalance in endothelial cells in vitro." in: Thrombosis research, Vol. 135, Issue 6, pp. 1154-9, (2015) (PubMed).
: "Antithrombin III is probably not a suitable biomarker for diagnosis of primary central nervous system lymphoma." in: Annals of hematology, Vol. 94, Issue 7, pp. 1167-74, (2015) (PubMed).
: "The anticoagulant effect of PGI2S and tPA in transgenic umbilical vein endothelial cells is linked to up-regulation of PKA and PKC." in: International journal of molecular sciences, Vol. 15, Issue 2, pp. 2826-39, (2014) (PubMed).
: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).
: "Development of a recombinant antithrombin variant as a potent antidote to fondaparinux and other heparin derivatives." in: Blood, Vol. 117, Issue 6, pp. 2054-60, (2011) (PubMed).
: "Neutralization of plasminogen activator inhibitor I (PAI-1) by the synthetic antagonist PAI-749 via a dual mechanism of action." in: Molecular pharmacology, Vol. 72, Issue 4, pp. 897-906, (2007) (PubMed).
Synonyms and alternative names related to SERPINC1
serpin family C member 1 (SERPINC1), antithrombin-III (CpipJ_CPIJ000472), antithrombin-III (CpipJ_CPIJ013111), serpin family C member 1 (Serpinc1), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), AI114908, ANTITHROMBIN, AT-III, At-3, AT-III, AT3, At3, AT3D, ATIII, DKFZp470C1733, SERPINC1, THPH7Protein level used designations for SERPINC1
- antithrombin-III
- serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
- serpin peptidase inhibitor, clade C (antithrombin), member 1
- Antithrombin-III
- anti-thrombin 3
- antithrombin
- serpin C1
- serpin peptidase inhibitor, clade C, member 1
- ATIII
- antithrombin III
- serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
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