SERF1A 产品
(Small EDRK-Rich Factor 1A (Telomeric) (SERF1A))
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This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known\; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. [provided by RefSeq, Jul 2008].
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Featured SERF1A Categories
Recommended SERF1A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7169839
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB
Validations
- (1)
Cat. No.
ABIN6750136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Monkey, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6750135
Quantity
100 μL
Datasheet
Datasheet
Recommended SERF1A 蛋白
Synonyms and alternative names related to SERF1A
small EDRK-rich factor 1A (SERF1A), small EDRK-rich factor 1 (Serf1), small EDRK-rich factor 1A (telomeric) (SERF1A), 4F5, FAM2A, H4F5, m4F5, Msmac1, SERF1, SERF1B, SMAM1Protein level used designations for SERF1A
- SMA modifier 1
- protein 4F5
- small EDRK-rich factor 1
- spinal muscular atrophy-related gene H4F5
- modifier of spinal muscular atrophy candidate 1
- small EDRK-rich factor 1A, telomeric
- small EDRK-rich factor 1B (centromeric)
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