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SENP6 抗体

(SUMO1/sentrin Specific Protease 6 (SENP6))
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA\; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009].
SENP6 抗体  (AA 1-110) SENP6 抗体  (AA 1-110) SENP6 抗体 (AA 1-110) (ABIN565219)

SENP6 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 4B7 unconjugated

SENP6 抗体  (Internal Region) SENP6 抗体  (Internal Region) SENP6 抗体 (Internal Region) (ABIN334488)

Verified SENP6 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

SENP6 抗体  (C-Term) SENP6 抗体  (C-Term) SENP6 抗体 (C-Term) (ABIN388052)

SENP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0664 unconjugated

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SENP6 抗体 by 抗原表位

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SENP6 抗体 by 克隆形成能力

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Popular SENP6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (3)
  • (4)
Cat. No. ABIN565219
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (3)
Cat. No. ABIN334488
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (3)
Cat. No. ABIN388052
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7192310
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Horse, Human, Pig
Application WB
Validations
  • (3)
Cat. No. ABIN2784245
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7004615
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7168841
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN6264987
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Horse, Human
Application WB
Validations
  • (1)
Cat. No. ABIN6738727
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7270635
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7185518
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7168843
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168842
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168844
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
Cat. No. ABIN6748763
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SENP6 抗体

Haahr, Borgermann, Guo, Typas, Achuthankutty, Hoffmann, Shearer, Sixma, Mailand: "ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability." in: Molecular cell, Vol. 70, Issue 1, pp. 165-174.e6, (2019) (PubMed).

Liu, Chen, Wang, Li, Wang: "Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6." in: PLoS pathogens, Vol. 9, Issue 6, pp. e1003480, (2013) (PubMed).

Lee, Lee, Park, Kang, Yoo, Ka, Oh, Jeon, Chung: "SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage." in: The EMBO journal, Vol. 31, Issue 23, pp. 4441-52, (2012) (PubMed).

Dou, Huang, Singh, Carpenter, Yeh: "Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex." in: Molecular cell, Vol. 39, Issue 3, pp. 333-45, (2010) (PubMed).

Han, Huang, Sun, Xiang, Wang, Yeh, Chen, Li, Shi, Cang, Sun, Wang, Wang, Gao, Yi: "SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12906-15, (2010) (PubMed).

Choi, Chung, Rho, Lee, Lee, Choi, Seol, Baek, Bang, Chung: "Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30669-77, (2006) (PubMed).

Jones, Fusi, Higham, Abdel-Hafiz, Horwitz, Lam, Brosens: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).

Bailey, OHare: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Aliases for SENP6 抗体

SUMO1/sentrin specific peptidase 6 (SENP6) 抗体
SUMO/sentrin specific peptidase 6 (Senp6) 抗体
SUMO1/sentrin specific peptidase 6 (Senp6) 抗体
SUMO1/sentrin specific peptidase 6a (senp6a) 抗体
2810017C20Rik 抗体
E130319N12Rik 抗体
fc83h02 抗体
im:7148342 抗体
mKIAA0797 抗体
SSP1 抗体
SUSP1 抗体
Susp1 抗体
wu:fc83h02 抗体
zgc:171230 抗体
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