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Sema4a 蛋白

(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))

This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].

recommended

Sema4a Protein (AA 1-761) (GST tag) (ABIN1319469)

Sema4a 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

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recommended

Sema4a Protein (AA 33-132) (GST tag) (ABIN1319471)

Sema4a 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

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recommended

Sema4a Protein (His tag) (ABIN7320641)

Sema4a 宿主: 小鼠宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE

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Sema4a 蛋白 by Origin

Find Sema4a 蛋白 for a variety of species such as anti-Human Sema4a, anti-Mouse Sema4a. The species listed below are among those available. Click on a link to go to the corresponding products.

Sema4a 蛋白 by Source

Here you will find Sema4a 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Sema4a 蛋白 by 蛋白类型

Here you can find Sema4a 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Sema4a 蛋白 by 应用范围

Find Sema4a 蛋白 validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Sema4a 蛋白 by 生物活性

Find Sema4a 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular Sema4a 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Sema4a Protein (AA 1-761) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319469

Quantity 10 μg

Datasheet Datasheet

Sema4a Protein (AA 33-132) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319471

Quantity 10 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN7320641

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (AA 33-683) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2181737

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Fc Tag,His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7520489

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7386176

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317490

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317489

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (AA 33-682) (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN4371022

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (AA 1-676) (Fc Tag)

Reactivity Mouse

Source CHO Cells

Validations

Cat. No. ABIN6253441

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2731626

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our Sema4a 蛋白

Chiou, Lucassen, Sather, Kallianpur, Connor: "Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis." in: Glia, Vol. 66, Issue 7, pp. 1317-1330, (2018) (PubMed).

Peng, Gao, Chong, Liu, Zhang: "Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor." in: Journal of biosciences, Vol. 40, Issue 5, pp. 855-62, (2015) (PubMed).

Mogie, Shanks, Nkyimbeng-Takwi, Smith, Davila, Lipsky, DeTolla, Keegan, Chapoval: "Neuroimmune semaphorin 4A as a drug and drug target for asthma." in: International immunopharmacology, Vol. 17, Issue 3, pp. 568-75, (2013) (PubMed).

Aliases for Sema4a 蛋白

semaphorin 4A (SEMA4A) 蛋白
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (sema4a) 蛋白
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a) 蛋白
semaphorin 4A (Sema4a) 蛋白
AI132332 蛋白
CORD10 蛋白
RP35 蛋白
SEMA4A 蛋白
SEMAB 蛋白
Semab 蛋白
SEMB 蛋白
SemB 蛋白

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Sema4a 蛋白 by Origin

Sema4a 蛋白 by Source

Sema4a 蛋白 by 蛋白类型

Sema4a 蛋白 by 应用范围

Sema4a 蛋白 by 生物活性

Popular Sema4a 蛋白

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Aliases for Sema4a 蛋白

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