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SCN2A 抗体

(Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
SCN2A 抗体  (Internal Region) SCN2A 抗体  (Internal Region) SCN2A 抗体 (Internal Region) (ABIN6263502)

SCN2A 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

SCN2A 抗体  (Intracellular) SCN2A 抗体  (Intracellular) SCN2A 抗体 (Intracellular) (ABIN7043641)

SCN2A 适用: 人, 大鼠, 小鼠 IHC, WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

SCN2A 抗体  (AA 273-362) SCN2A 抗体  (AA 273-362) SCN2A 抗体 (AA 273-362) (ABIN520021)

SCN2A 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated

SCN2A 抗体 by 适用

Find SCN2A 抗体 for a variety of species such as anti-Human SCN2A, anti-Rat SCN2A, anti-Mouse SCN2A. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find SCN2A 抗体 validated for a specific application such as IF (cc), IF (p), IHC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find SCN2A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find SCN2A 抗体 with a specific conjugate such as Biotin, AbBy Fluor® 350, AbBy Fluor® 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SCN2A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN6263502
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB, IF, IP, ICC
Validations
  • (3)
Cat. No. ABIN7043641
Quantity 25 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN520021
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6147435
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IHC, WB, IP, FM
Validations
  • (2)
Cat. No. ABIN6658123
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB, IF
Validations
  • (2)
Cat. No. ABIN7043640
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN735938
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN735940
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN914528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN914532
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN914531
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN2806220
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5010277
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5010276
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN914529
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SCN2A 抗体

Gazina, Leaw, Richards, Wimmer, Kim, Aumann, Featherby, Churilov, Hammond, Reid, Petrou: "'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour." in: Human molecular genetics, Vol. 24, Issue 5, pp. 1457-68, (2015) (PubMed).

Wildburger, Ali, Hsu, Shavkunov, Nenov, Lichti, LeDuc, Mostovenko, Panova-Elektronova, Emmett, Nilsson, Laezza: "Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 5, pp. 1288-300, (2015) (PubMed).

Hamada, Kole: "Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7272-86, (2015) (PubMed).

Wimmer, Harty, Richards, Phillips, Miyazaki, Nukina, Petrou: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).

Liu, Deng, Wang, Zhang, Luo, Yan, Su, Liu: "KCNE2 modulates cardiac L-type Ca(2+) channel." in: Journal of molecular and cellular cardiology, Vol. 72, pp. 208-18, (2014) (PubMed).

Baek, Rubinstein, Scheuer, Trimmer: "Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures." in: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15363-73, (2014) (PubMed).

Wang, Hooks, Sun: "Thorough GABAergic innervation of the entire axon initial segment revealed by an optogenetic 'laserspritzer'." in: The Journal of physiology, Vol. 592, Issue Pt 19, pp. 4257-76, (2014) (PubMed).

Li, Tian, Scalmani, Frassoni, Mantegazza, Wang, Yang, Wu, Shu: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).

Tian, Wang, Ke, Guo, Shu: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).

Martínez-Hernández, Ballesteros-Merino, Fernández-Alacid, Nicolau, Aguado, Luján: "Polarised localisation of the voltage-gated sodium channel Na(v)1.2 in cerebellar granule cells." in: Cerebellum (London, England), Vol. 12, Issue 1, pp. 16-26, (2013) (PubMed).

Aliases for SCN2A 抗体

sodium voltage-gated channel alpha subunit 2 (SCN2A) 抗体
sodium channel protein type 2 subunit alpha (LOC100217927) 抗体
sodium channel protein type 2 subunit alpha (LOC100389294) 抗体
sodium channel protein type 2 subunit alpha (LOC100484218) 抗体
sodium channel, voltage-gated, type II, alpha (Scn2a) 抗体
sodium voltage-gated channel alpha subunit 2 (Scn2a) 抗体
sodium channel protein type 2 subunit alpha (LOC478773) 抗体
sodium channel, voltage-gated, type II, alpha subunit (SCN2A) 抗体
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