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SCN1B 产品

(Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

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Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

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Featured SCN1B Categories

SCN1B 抗体

High quality antibodies with extensive validation data.

SCN1B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SCN1B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7169933
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654602
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN954692
Quantity 0.4 mL
Datasheet Datasheet

Recommended SCN1B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319273
Quantity 10 μg
Datasheet Datasheet
Reactivity Rabbit
Source Yeast
Validations
Cat. No. ABIN1473305
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1619654
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SCN1B Products

Baroni, Picco, Barbieri, Moran: "Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 106, Issue 1, pp. 13-29, (2014) (PubMed).

Barbieri, Baroni, Moran: "Identification of an intra-molecular disulfide bond in the sodium channel ?1-subunit." in: Biochemical and biophysical research communications, Vol. 420, Issue 2, pp. 364-7, (2012) (PubMed).

Chen, Westenbroek, Xu, Edwards, Sorenson, Chen, McEwen, OMalley, Bharucha, Meadows, Knudsen, Vilaythong, Noebels, Saunders, Scheuer, Shrager, Catterall, Isom: "Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 16, pp. 4030-42, (2004) (PubMed).

Synonyms and alternative names related to SCN1B

sodium channel, voltage-gated, type I, beta (Scn1b), sodium voltage-gated channel beta subunit 1 (Scn1b), sodium voltage-gated channel beta subunit 1 (SCN1B), GEFSP1

Protein level used designations for SCN1B

  • sodium channel subunit beta-1
  • sodium channel, voltage-gated, type I, beta polypeptide
  • sodium channel voltage-gated type 1 beta polypeptide
  • sodium channel voltage-gated type I beta polypeptide
  • sodium channel, voltage-gated, type 1, beta polypeptide
  • sodium channel beta-1 subunit
  • sodium channel beta 1-subunit
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