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Sclerostin 抗体

(Sclerostin (SOST))
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].
Sclerostin 抗体  (N-Term) Sclerostin 抗体  (N-Term) Sclerostin 抗体 (N-Term) (ABIN390193)

SOST 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12388 unconjugated

Sclerostin 抗体  (AA 25-213) Sclerostin 抗体  (AA 25-213) Sclerostin 抗体 (AA 25-213) (ABIN7435190)

SOST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

Sclerostin 抗体  (AA 24-213) Sclerostin 抗体  (AA 24-213) Sclerostin 抗体 (AA 24-213) (ABIN7168635)

SOST 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Sclerostin 抗体 by Grade

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Sclerostin 抗体 by 适用

Find Sclerostin 抗体 for a variety of species such as anti-Human Sclerostin, anti-Mouse Sclerostin, anti-Rat Sclerostin. The species listed below are among those available. Click on a link to go to the corresponding products.

Sclerostin 抗体 by 应用范围

Find Sclerostin 抗体 validated for a specific application such as WB, ELISA, IF (p), IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Sclerostin 抗体 by 抗原表位

Find Sclerostin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Sclerostin 抗体 by 克隆形成能力

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Sclerostin 抗体 by 克隆

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Sclerostin 抗体 by 标记

Find Sclerostin 抗体 with a specific conjugate such as Biotin, HRP, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Sclerostin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN390193
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN7435190
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7168635
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7168634
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IF (p), ICC, IHC (p), IF (cc), IHC (fro)
Validations
  • (2)
Cat. No. ABIN1714867
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), EIA
Validations
  • (1)
  • (2)
Cat. No. ABIN358751
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7435193
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Dog, Horse, Human, Monkey, Pig
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2628623
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN2613479
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN390194
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN1539331
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN358752
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN7091679
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Pig, Rat
Application WB, IF (p), IHC (p)
Validations
Cat. No. ABIN715586
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN7091678
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Sclerostin 抗体

Sun, Zhang, Chen, Ji, Ma, Qiao, Wu, Zhou, Bu, Zhu, Zhang, Jiang, Liu, Li, Liu, Yang, Liu: "Targeting SOST using a small-molecule compound retards breast cancer bone metastasis." in: Molecular cancer, Vol. 21, Issue 1, pp. 228, (2023) (PubMed).

Zarei, Hulley, Sabokbar, Javaid: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).

Sato, Cregor, Delgado-Calle, Condon, Allen, Peacock, Plotkin, Bellido: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).

Lin, Lin, Chang, Wang, Lai: "Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation." in: Bioelectromagnetics, Vol. 36, Issue 7, pp. 494-505, (2015) (PubMed).

Ellies, Viviano, McCarthy, Rey, Itasaki, Saunders, Krumlauf: "Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 21, Issue 11, pp. 1738-49, (2006) (PubMed).

Semenov, He: "LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38276-84, (2006) (PubMed).

Balemans, Van Hul: "Human genetics of SOST." in: Journal of musculoskeletal & neuronal interactions, Vol. 6, Issue 4, pp. 355-6, (2006) (PubMed).

Aliases for Sclerostin 抗体

sclerostin (LOC100313724) 抗体
sclerostin (SOST) 抗体
sclerostin (Sost) 抗体
5430411E23Rik 抗体
CDD 抗体
LOC100313724 抗体
VBCH 抗体
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