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S100A8 产品

(S100 Calcium Binding Protein A8 (S100A8))

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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008].

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Featured S100A8 Categories

S100A8 抗体

High quality antibodies with extensive validation data.

S100A8 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

S100A8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended S100A8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7434065
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7443995
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7270129
Quantity 100 μL
Datasheet Datasheet

Recommended S100A8 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (6)
Cat. No. ABIN6574287
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6959243
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962252
Quantity 96 tests
Datasheet Datasheet

Recommended S100A8 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7275540
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (5)
  • (1)
Cat. No. ABIN1319072
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319074
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our S100A8 Products

Angioni, Sasset, Cioccarelli, Sánchez-Rodríguez, Bertoldi, Putaggio, Viola, Cattelan, Molon: "COVID-19 Vaccination Limits Systemic Danger Signals in SARS-CoV-2 Infected Patients." in: , Vol. 14, Issue 3, (2022) (PubMed).

Shao, Fang, Dang, Xue, Zhang, Li, Qiao, Cao, Zhuang, Shen, Zhang, Qiao, Li, Gudjonsson, Wang: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." in: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).

Laulund, Trøstrup, Lerche, Thomsen, Christophersen, Calum, Høiby, Moser: "Synergistic effect of immunomodulatory S100A8/A9 and ciprofloxacin against Pseudomonas aeruginosa biofilm in a murine chronic wound model." in: Pathogens and disease, Vol. 78, Issue 5, (2020) (PubMed).

Yu, Zhang, Zang, Zeng, Zuo, Bai, Liu, Sun, Liu: "iTRAQ-based quantitative protein expression profiling of biomarkers in childhood B-cell and T-cell acute lymphoblastic leukemia." in: Cancer management and research, Vol. 11, pp. 7047-7063, (2019) (PubMed).

Inoue, Shirakawa, Togashi, Tajima, Okuyama, Kyohara, Tanaka, Orime, Saisho, Yamada, Shibue, Kulkarni, Terauchi: "Signaling between pancreatic β cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation." in: The Journal of biological chemistry, Vol. 293, Issue 16, pp. 5934-5946, (2019) (PubMed).

Ma, Sun, Zhang, Zhang, Yao: "Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 31-38, (2018) (PubMed).

Tajmul, Parween, Singh, Mathur, Sharma, Kumar, Sharma, Yadav: "Identification and validation of salivary proteomic signatures for non-invasive detection of ovarian cancer." in: International journal of biological macromolecules, Vol. 108, pp. 503-514, (2018) (PubMed).

Kovačić, Mitrović-Ajtić, Beleslin-Čokić, Djikić, Subotički, Diklić, Leković, Gotić, Mossuz, Čokić: "TLR4 and RAGE conversely mediate pro-inflammatory S100A8/9-mediated inhibition of proliferation-linked signaling in myeloproliferative neoplasms." in: Cellular oncology (Dordrecht), Vol. 41, Issue 5, pp. 541-553, (2018) (PubMed).

Trøstrup, Lerche, Christophersen, Jensen, Høiby, Moser: "Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds." in: International journal of molecular sciences, Vol. 18, Issue 7, (2018) (PubMed).

Gruda, Ruggeberg, OSullivan, Guliashvili, Scheirer, Golobish, Capponi, Chan: "Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads." in: PLoS ONE, Vol. 13, Issue 1, pp. e0191676, (2017) (PubMed).

Synonyms and alternative names related to S100A8

S100 calcium binding protein A8 (S100A8), S100 calcium binding protein A8 (S100a8), S100 calcium binding protein A8 (calgranulin A) (S100a8), 60B8AG, 60B8Ag, AI323541, B8Ag, CAGA, Caga, CFAG, CFAg, CGLA, CP-10, L1Ag, MA387, MIF, MRP-8, MRP8, Mrp8, NIF, P8, p8, S100A8

Protein level used designations for S100A8

  • MRP-8
  • S100 calcium-binding protein A8 (calgranulin A)
  • calgranulin A
  • calgranulin-A
  • calprotectin L1L subunit
  • cystic fibrosis antigen
  • leukocyte L1 complex light chain
  • migration inhibitory factor-related protein 8
  • protein S100-A8
  • urinary stone protein band A
  • S100 calcium binding protein A8 (calgranulin A)
  • p8
  • S100 calcium binding protein A8
  • BEE11
  • P7
  • S100 calcium-binding protein A8
  • neutrophil cytosolic 7 kDa protein
  • calprotectin
  • chemotactic S100 protein
  • chemotactic cytokine CP-10
  • pro-inflammatory S100 cytokine
  • macrophage migration inhibitory factor-related protein-8
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