SAV1 抗体
(Salvador Homolog 1 (SAV1))
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012].
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SAV1 抗体 by Grade
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SAV1 抗体 by 适用
Find SAV1 抗体 for a variety of species such as anti-Human SAV1, anti-Mouse SAV1, anti-Rat SAV1. The species listed below are among those available. Click on a link to go to the corresponding products.
SAV1 抗体 by 应用范围
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SAV1 抗体 by 抗体来源
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SAV1 抗体 by 抗原表位
Find SAV1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
SAV1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SAV1 抗体. Click on a link to go to the corresponding products.
SAV1 抗体 by 克隆
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SAV1 抗体 by 标记
Find SAV1 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular SAV1 抗体
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Validations
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Datasheet
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Application
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Quantity
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Quantity
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Datasheet
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Quantity
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Datasheet
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Quantity
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Datasheet
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Quantity
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Datasheet
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Application
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Quantity
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Quantity
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Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
ABIN2580122
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
Cat. No.
ABIN2580121
Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Quantity
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Datasheet
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Latest Publications for our SAV1 抗体
: "Hippo pathway deficiency reverses systolic heart failure after infarction." in: Nature, Vol. 550, Issue 7675, pp. 260-264, (2018) (PubMed).: "Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway." in: The Journal of pathology, Vol. 239, Issue 1, pp. 97-108, (2016) (PubMed).
: "Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma." in: Translational oncology, Vol. 7, Issue 2, pp. 309-21, (2014) (PubMed).
: "Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPAR?." in: PLoS ONE, Vol. 7, Issue 1, pp. e30983, (2012) (PubMed).
: "Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system." in: Molecular biology reports, Vol. 39, Issue 8, pp. 8225-30, (2012) (PubMed).
: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).
: "Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction." in: Nature cell biology, Vol. 12, Issue 12, pp. 1166-76, (2010) (PubMed).
: "Mutational analysis of salvador gene in human carcinomas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 111, Issue 6, pp. 595-8, (2003) (PubMed).
Aliases for SAV1 抗体
salvador family WW domain containing protein 1 (SAV1) 抗体salvador family WW domain containing 1 (Sav1) 抗体
salvador family WW domain containing protein 1 (Sav1) 抗体
1700040G09Rik 抗体
Salv 抗体
SAV 抗体
Sav 抗体
WW45 抗体
Wwp3 抗体
WWP4 抗体
Wwp4 抗体
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