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SARS-CoV-2 NSP1 产品

(SARS-CoV-2 Host Translation Inhibitor Nsp1 (NSP1))

Categories

Inhibits host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation. By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.

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Recommended SARS-CoV-2 NSP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Application WB
Validations
  • (1)
Cat. No. ABIN7272996
Quantity 300 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Application ELISA
Validations
Cat. No. ABIN6990007
Quantity 0.1 mg
Datasheet Datasheet

Recommended SARS-CoV-2 NSP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6952638
Quantity 100 μg
Datasheet Datasheet

Synonyms and alternative names related to SARS-CoV-2 NSP1

ORF1a polyprotein;ORF1ab polyprotein (ORF1ab), pp1ab

Protein level used designations for SARS-CoV-2 NSP1

  • ORF1ab polyprotein
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