SARS-CoV-2 NSP1 产品
(SARS-CoV-2 Host Translation Inhibitor Nsp1 (NSP1))
Categories
Inhibits host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation. By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.
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Recommended SARS-CoV-2 NSP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Application
WB
Validations
- (1)
Cat. No.
ABIN7272996
Quantity
300 μg
Datasheet
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Application
ELISA
Validations
Cat. No.
ABIN6990007
Quantity
0.1 mg
Datasheet
Datasheet
Recommended SARS-CoV-2 NSP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6952638
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to SARS-CoV-2 NSP1
ORF1a polyprotein;ORF1ab polyprotein (ORF1ab), pp1abProtein level used designations for SARS-CoV-2 NSP1
- ORF1ab polyprotein
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