SAE1 产品
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Categories
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
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Featured SAE1 Categories
SAE1 抗体
High quality antibodies with extensive validation data.
SAE1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SAE1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Cat. No.
ABIN564342
Quantity
100 μg
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Cat. No.
ABIN2856922
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100 μL
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Recommended SAE1 ELISA试剂盒
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ABIN1160099
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96 tests
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Latest Publications for our SAE1 Products
: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).: "Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort." in: Annals of the rheumatic diseases, Vol. 72, Issue 1, pp. 151-3, (2012) (PubMed).
: "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." in: The EMBO journal, Vol. 24, Issue 3, pp. 439-51, (2005) (PubMed).
: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).
: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).
: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).
: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).
: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).
: "Differential interactions of Id proteins with basic-helix-loop-helix transcription factors." in: The Journal of biological chemistry, Vol. 272, Issue 32, pp. 19785-93, (1997) (PubMed).
: "The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein." in: Genes & development, Vol. 8, Issue 11, pp. 1270-84, (1994) (PubMed).
Synonyms and alternative names related to SAE1
SUMO1 activating enzyme subunit 1 (SAE1), SUMO1 activating enzyme subunit 1 (Sae1), SUMO1 activating enzyme subunit 1 L homeolog (sae1.L), SUMO1 activating enzyme subunit 1 (sae1), 2400010M20Rik, 2610044L12Rik, AL033372, aos, AOS1, Aos1p, AW743391, D7Ertd177e, HSPC140, sae2a, SUA1, Sua1, Sua1p, UBLE1A, Uble1a, uble1a, wu:fa28b04, zgc:86633Protein level used designations for SAE1
- SUMO-1 activating enzyme E1 N subunit
- SUMO-1 activating enzyme subunit 1
- SUMO-activating enzyme subunit 1
- activator of SUMO1
- sentrin/SUMO-activating protein AOS1
- ubiquitin-like 1-activating enzyme E1A
- ubiquitin-like protein SUMO-1 activating enzyme
- ubiquitin-like (sentrin) activating enzyme E1A
- ubiquitin-like 1 (sentrin) activating enzyme E1A
- ubiquitin-like 1 (sentrin) activating enzyme subunit 1
- SUMO-activating enzyme E1 N subunit
- SUMO1 activating enzyme subunit 2a
- Ubiquitin-like 1-activating enzyme E1A
- fa28b04
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