RUNX1T1 产品
(Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
Categories
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
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Featured RUNX1T1 Categories
RUNX1T1 抗体
High quality antibodies with extensive validation data.
RUNX1T1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RUNX1T1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RUNX1T1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, ChIP
Validations
- (6)
Cat. No.
ABIN6655575
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN560190
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7165188
Quantity
100 μg
Datasheet
Datasheet
Recommended RUNX1T1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969697
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1150734
Quantity
96 tests
Datasheet
Datasheet
Recommended RUNX1T1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318994
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318996
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093943
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RUNX1T1 Products
: "Sperm chromatin proteomics identifies evolutionarily conserved fertility factors." in: Nature, Vol. 443, Issue 7107, pp. 101-5, (2006) (PubMed).: "RNA helicases: regulators of differentiation." in: Clinical biochemistry, Vol. 38, Issue 6, pp. 499-503, (2005) (PubMed).
: "Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. ..." in: Nature biotechnology, Vol. 23, Issue 3, pp. 344-8, (2005) (PubMed).
: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." in: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
: "VASA is a specific marker for both normal and malignant human germ cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 2, pp. 159-66, (2002) (PubMed).
Synonyms and alternative names related to RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1), RUNX1 translocation partner 1 L homeolog (runx1t1.L), RUNX1 translocation partner 1 (RUNX1T1), runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1), RUNX1 translocation partner 1 (Runx1t1), AML1T1, CBFA2T1, Cbfa2t1, Cbfa2t1h, CDR, ETO, MTG8, si:ch211-232j17.1, wu:fi14b07, zgc:154044, ZMYND2Protein level used designations for RUNX1T1
- protein CBFA2T1
- MTG8
- MTG8/ETOb
- expressed during postmitotic spinal neurons, most likely in motorneurons
- acute myelogenous leukemia 1 translocation 1, cyclin-D related
- core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
- eight twenty one protein
- myeloid translocation gene on 8q22
- zinc finger MYND domain-containing protein 2
- CBFA2T1 identified gene homolog
- acute myelogenous leukemia 1 translocation 1 protein
- core-binding factor, runt domain, alpha subunit 2
- cyclin D-related
- translocated to, 1
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