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RTEL1 产品

(Regulator of Telomere Elongation Helicase 1 (RTEL1))

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In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. In addition, Rtel is required for telomere elongation. Therefore, the mouse Rtel gene regulates chromosome stability and telomere length. This gene is the human ortholog of the mouse Rtel gene, so its protein product may play similar roles in humans. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B), generates a non-coding transcript. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].

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RTEL1 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our RTEL1 Products

Chan, Fugger, West: "Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations." in: Nature cell biology, Vol. 20, Issue 1, pp. 92-103, (2018) (PubMed).

Synonyms and alternative names related to RTEL1

regulator of telomere elongation helicase 1 (RTEL1), regulator of telomere elongation helicase 1 (rtel1), RAD3-like DNA-binding helicase protein (AT1G79950), regulator of telomere elongation helicase 1 (LOC100286037), regulator of telomere elongation helicase 1 (Rtel1), AI451565, AW540478, bK3184A7.3, C20orf41, DKCB5, F18B13.3, F18B13_3, NHL, RGD1306721, RTEL, Rtel, zgc:113114

Protein level used designations for RTEL1

  • regulator of telomere elongation helicase 1
  • helicase-like protein NHL
  • regulator of telomere length
  • DEAH helicase
  • regulator of telomere length helicase 1
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