RSPO1 产品
(R-Spondin 1 (RSPO1))
Categories
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. [provided by RefSeq, Jul 2008].
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Featured RSPO1 Categories
RSPO1 抗体
High quality antibodies with extensive validation data.
RSPO1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RSPO1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RSPO1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7430144
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7430147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7437200
Quantity
100 μL
Datasheet
Datasheet
Recommended RSPO1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959020
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975875
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999503
Quantity
96 tests
Datasheet
Datasheet
Recommended RSPO1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
CHO Cells
Validations
- (3)
Cat. No.
ABIN7275537
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275538
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN2181686
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our RSPO1 Products
: "NAD+ supplementation rejuvenates aged gut adult stem cells." in: Aging cell, Vol. 18, Issue 3, pp. e12935, (2020) (PubMed).: "Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging." in: Cell stem cell, Vol. 22, Issue 5, pp. 769-778.e4, (2019) (PubMed).
: "AhR activation by 6-formylindolo[3,2-b]carbazole and 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibit the development of mouse intestinal epithelial cells." in: Environmental toxicology and pharmacology, Vol. 43, pp. 44-53, (2017) (PubMed).
: "The association of radiographic progression with serum R-spondin 1 (RSPO1) levels or Dickkopf-1 (DKK1)/RSPO1 ratios in rheumatoid arthritis patients: clinical evidence for reciprocal inhibition ..." in: Scandinavian journal of rheumatology, Vol. 43, Issue 6, pp. 453-61, (2014) (PubMed).
: "Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression." in: The Journal of biological chemistry, Vol. 288, Issue 21, pp. 15131-41, (2013) (PubMed).
: "Reconstitution of R-spondin:LGR4:ZNRF3 adult stem cell growth factor signaling complexes with recombinant proteins produced in Escherichia coli." in: Biochemistry, Vol. 52, Issue 41, pp. 7295-304, (2013) (PubMed).
: "Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins." in: The Journal of experimental medicine, Vol. 210, Issue 6, pp. 1201-16, (2013) (PubMed).
: "Syndromic true hermaphroditism due to an R-spondin1 (RSPO1) homozygous mutation." in: Human mutation, Vol. 29, Issue 2, pp. 220-6, (2008) (PubMed).
: "R-spondin1 is essential in sex determination, skin differentiation and malignancy." in: Nature genetics, Vol. 38, Issue 11, pp. 1304-9, (2006) (PubMed).
: "A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids." in: Stem cell reports, Vol. 10, Issue 1, pp. 314-328 (PubMed).
Synonyms and alternative names related to RSPO1
R-spondin 1 (Rspo1), R-spondin 1 (RSPO1), R-spondin 1 (LOC100049655), R-spondin 1 (rspo1), CRISTIN3, R-spondin, RGD1565558, RSPO, Rspondin, wu:fj81e05, zgc:92153Protein level used designations for RSPO1
- R-spondin-1
- R-spondin homolog
- roof plate-specific spondin-1
- R-spondin1
- cristin-3
- cysteine-rich and single thrombospondin domain-containing protein 3
- mCristin-3
- thrombospondin type 1 domain containing gene Rspondin
- ovarian R-spondin member 1
- Roof plate-specific spondin-1
- cb1071
- fj81e05
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