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RPRD1B 产品

(Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))

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Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation (By similarity).

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Featured RPRD1B Categories

RPRD1B 抗体

High quality antibodies with extensive validation data.

RPRD1B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPRD1B 抗体

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Quantity 100 μg
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Cat. No. ABIN7167582
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Recommended RPRD1B ELISA试剂盒

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Reactivity Human
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Recommended RPRD1B 蛋白

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Synonyms and alternative names related to RPRD1B

regulation of nuclear pre-mRNA domain containing 1B (rprd1b), regulation of nuclear pre-mRNA domain containing 1B L homeolog (rprd1b.L), regulation of nuclear pre-mRNA domain containing 1B (RPRD1B), regulation of nuclear pre-mRNA domain containing 1B (Rprd1b), 2610304G08Rik, 2810446G03Rik, C13H20ORF77, C20orf77, CREPT, Crept, dJ1057B20.2, fb23h08, MGC130705, NET60, RGD1304782, rprd1ba, wu:fb23h08, zgc:55687

Protein level used designations for RPRD1B

  • regulation of nuclear pre-mRNA domain-containing protein 1B
  • unm hi3400
  • un-named hi3400
  • regulation of nuclear pre-mRNA domain containing 1B
  • regulation of nuclear pre-mRNA domain containing 1B a
  • Regulation of nuclear pre-mRNA domain containing 1B
  • cell cycle-related and expression-elevated protein in tumor
  • cell-cycle related and expression-elevated protein in tumor
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