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RORC 产品

(RAR-Related Orphan Receptor C (RORC))

Categories

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known\; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RORC Categories

RORC 抗体

High quality antibodies with extensive validation data.

RORC ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RORC 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RORC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (5)
Cat. No. ABIN7439402
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF
Validations
  • (4)
Cat. No. ABIN625825
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN2782284
Quantity 100 μL
Datasheet Datasheet

Recommended RORC ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969831
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969832
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959047
Quantity 96 tests
Datasheet Datasheet

Recommended RORC 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318464
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318462
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423876
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RORC Products

van Baarsen, Lebre, van der Coelen, Aarrass, Tang, Ramwadhdoebe, Gerlag, Tak et al.: "Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for ..." in: Arthritis research & therapy, Vol. 16, Issue 4, pp. 426, (2015) (PubMed).

Wongkajornsilp, Wamanuttajinda, Kasetsinsombat, Duangsa-ard, Sa-ngiamsuntorn, Hongeng, Maneechotesuwan: "Sunitinib indirectly enhanced anti-tumor cytotoxicity of cytokine-induced killer cells and CD3⁺CD56⁺ subset through the co-culturing dendritic cells." in: PLoS ONE, Vol. 8, Issue 11, pp. e78980, (2013) (PubMed).

Zielinski, Mele, Aschenbrenner, Jarrossay, Ronchi, Gattorno, Monticelli, Lanzavecchia, Sallusto: "Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β." in: Nature, Vol. 484, Issue 7395, pp. 514-8, (2012) (PubMed).

Verma, Dempsey, Long, Davies, Barry, Fallon, Volkov, Kelleher: "Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling." in: The Journal of biological chemistry, Vol. 287, Issue 32, pp. 27204-16, (2012) (PubMed).

Tosolini, Kirilovsky, Mlecnik, Fredriksen, Mauger, Bindea, Berger, Bruneval, Fridman, Pagès, Galon: "Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer." in: Cancer research, Vol. 71, Issue 4, pp. 1263-71, (2011) (PubMed).

Alonso, Wong, Zhang, Winer, Suhoski, Tolentino, Gaitan, Davidson, Kung, Galel, Nadeau, Kim, Utz, Söderström, Engleman: "T(H)1, T(H)2, and T(H)17 cells instruct monocytes to differentiate into specialized dendritic cell subsets." in: Blood, Vol. 118, Issue 12, pp. 3311-20, (2011) (PubMed).

Huang, Huang, Lee, Ng, Chang: "Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients." in: The Laryngoscope, Vol. 117, Issue 4, pp. 737-42, (2007) (PubMed).

Synonyms and alternative names related to RORC

RAR related orphan receptor C (RORC), RAR-related orphan receptor C (Rorc), RAR-related orphan receptor gamma (Rorc), NR1F3, Nr1f3, RORG, RORgamma, RZR-GAMMA, RZRG, Thor, TOR

Protein level used designations for RORC

  • RAR-related orphan nuclear receptor variant 2
  • nuclear receptor ROR-gamma
  • nuclear receptor RZR-gamma
  • nuclear receptor subfamily 1 group F member 3
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • RAR-related orphan receptor gamma
  • retinoid-related orphan receptor-gamma
  • thymus orphan receptor
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