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RORA 产品

(RAR-Related Orphan Receptor A (RORA))

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The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured RORA Categories

RORA 抗体

High quality antibodies with extensive validation data.

RORA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RORA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RORA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (3)
Cat. No. ABIN2857022
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2776008
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1049293
Quantity 50 μg
Datasheet Datasheet

Recommended RORA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959046
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5658351
Quantity 96 tests
Datasheet Datasheet

Recommended RORA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318456
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318454
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405298
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RORA Products

Yasui, Matsuzaki, Konno, Hirai: "Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia." in: Neuroscience, (2020) (PubMed).

Luo, Wang, Yeh, Sun, Liang, Xiao, Xu, Niu, Cheng, Maity, Jiang, Chang: "LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." in: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).

Brożyna, Jóźwicki, Skobowiat, Jetten, Slominski: "RORα and RORγ expression inversely correlates with human melanoma progression." in: Oncotarget, Vol. 7, Issue 39, pp. 63261-63282, (2018) (PubMed).

Strzelczyk, Gołąbek, Cuber, Krakowczyk, Owczarek, Fronczek, Choręża, Hudziec, Ostrowska: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." in: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).

Suyama, Silagi, Choi, Sakabe, Mochida, Shapiro, Risbud: "Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health." in: Oncotarget, Vol. 7, Issue 17, pp. 23056-71, (2016) (PubMed).

Li, Ying, Tong, Zhong, Su, Xiang, Shu, Rong, Xiong, Li, Chan, Ambinder, Guo, Tao: "Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas." in: Cellular and molecular life sciences : CMLS, Vol. 71, Issue 11, pp. 2179-92, (2014) (PubMed).

Barrett, Fang, Gargano, Markovich, Kocarek, Runge-Morris: "Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1505-13, (2013) (PubMed).

Benderdour, Fahmi, Beaudet, Fernandes, Shi: "Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts." in: Journal of cellular biochemistry, Vol. 112, Issue 8, pp. 2160-9, (2011) (PubMed).

Tordjman, Leroyer, Chauvet, Quette, Chauvet, Tomkiewicz, Chapron, Barouki, Forest, Aggerbeck, Antoine: "Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione." in: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23591-602, (2007) (PubMed).

Lechtken, Hörnig, Werz, Corvey, Zündorf, Dingermann, Brandes, Steinhilber: "Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro." in: Biochemical and biophysical research communications, Vol. 358, Issue 3, pp. 890-6, (2007) (PubMed).

Synonyms and alternative names related to RORA

RAR related orphan receptor A (RORA), RAR related orphan receptor A (rora), RAR-related orphan receptor A (Rora), RAR-related orphan receptor A, paralog a (roraa), RAR-related orphan receptor alpha (Rora), 9530021D13Rik, gb:dq017624, MGC146531, nmf267, nr1f1, NR1F1, Nr1f1, ror1, ROR1, ror2, ROR2, ror3, ROR3, rora2, RORalpha-B, RORalpha1, RZR-ALPHA, rzra, RZRA, sg, staggerer, tmgc26

Protein level used designations for RORA

  • nuclear receptor ROR-alpha
  • RAR-related orphan receptor A
  • RAR-related orphan receptor alpha
  • ROR-alpha
  • nuclear receptor RZR-alpha
  • nuclear receptor subfamily 1 group F member 1
  • retinoic acid receptor-related orphan receptor alpha
  • retinoid-related orphan receptor alpha
  • thyroid hormone nuclear receptor alpha variant 4
  • transcription factor RZR-alpha
  • NR1F1-B
  • retinoid-related orphan receptor alpha 2
  • rora
  • retinoid-related orphan receptor-alpha
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