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ROBO3 ELISA试剂盒

(Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS)\; an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated. [provided by RefSeq, Dec 2009].
ROBO3 ELISA 试剂盒 ROBO3 ELISA 试剂盒 ROBO3 ELISA 试剂盒 (ABIN4884368)

ROBO3 适用: 人 Colorimetric Sandwich ELISA 15-0.06 ng/mL Cell Culture Supernatant, Plasma, Serum

ROBO3 IQ-ELISA 试剂盒 (ABIN6384942)

ROBO3 适用: 人 qPCR Sandwich ELISA Cell Culture Supernatant, Plasma, Serum

ROBO3 ELISA 试剂盒 (ABIN6730276)

ROBO3 适用: 小鼠 Colorimetric Sandwich ELISA Cell Culture Supernatant, Cell Samples, Plasma, Serum, Tissue Lysate

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Popular ROBO3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4884368
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384942
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730276
Quantity 96 tests
Datasheet Datasheet

Aliases for ROBO3 ELISA试剂盒

roundabout guidance receptor 3 (ROBO3) ELISA试剂盒
roundabout 3 (robo3) ELISA试剂盒
roundabout guidance receptor 3 (Robo3) ELISA试剂盒
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