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ROBO3 抗体

(Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS)\; an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated. [provided by RefSeq, Dec 2009].
ROBO3 抗体  (AA 1-147) ROBO3 抗体  (AA 1-147) ROBO3 抗体 (AA 1-147) (ABIN528582)

ROBO3 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H1 unconjugated

ROBO3 抗体  (Internal Region) ROBO3 抗体  (Internal Region) ROBO3 抗体 (Internal Region) (ABIN190793)

Verified ROBO3 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated

ROBO3 抗体  (AA 1237-1386) ROBO3 抗体  (AA 1237-1386) ROBO3 抗体 (AA 1237-1386) (ABIN7168446)

ROBO3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

ROBO3 抗体 by Grade

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ROBO3 抗体 by 适用

Find ROBO3 抗体 for a variety of species such as anti-Human ROBO3, anti-Mouse ROBO3, anti-Cow ROBO3. The species listed below are among those available. Click on a link to go to the corresponding products.

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ROBO3 抗体 by 抗原表位

Find ROBO3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ROBO3 抗体 by 克隆形成能力

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ROBO3 抗体 by 克隆

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ROBO3 抗体 by 标记

Find ROBO3 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ROBO3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN528582
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN190793
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7168446
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7261161
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN528579
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (1)
Cat. No. ABIN5539585
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7270111
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC
Validations
Cat. No. ABIN7118720
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA
Validations
Cat. No. ABIN190792
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
Cat. No. ABIN7136342
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
Cat. No. ABIN5698300
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN5515113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6903013
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6846697
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6830634
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ROBO3 抗体

Bauer, Dowejko, Bosserhoff, Reichert, Bauer: "Slit-2 facilitates interaction of P-cadherin with Robo-3 and inhibits cell migration in an oral squamous cell carcinoma cell line." in: Carcinogenesis, Vol. 32, Issue 6, pp. 935-43, (2011) (PubMed).

Kato, Takeuchi, Sato, Yoneyama, Yamamoto, Matsui, Uematsu, Jung, Kawai, Ishii, Yamaguchi, Otsu, Tsujimura, Koh, Reis e Sousa, Matsuura, Fujita, Akira: "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses." in: Nature, Vol. 441, Issue 7089, pp. 101-5, (2006) (PubMed).

Aliases for ROBO3 抗体

roundabout guidance receptor 3 (ROBO3) 抗体
roundabout 3 (robo3) 抗体
roundabout guidance receptor 3 (Robo3) 抗体
robo3 (LOC658818) 抗体
roundabout guidance receptor 3 L homeolog (robo3.L) 抗体
roundabout, axon guidance receptor, homolog 3 (Drosophila) (robo3) 抗体
cb503 抗体
CG5423 抗体
CG14345 抗体
CT17158 抗体
DKFZp468G0223 抗体
DmelCG5423 抗体
dRobo-3 抗体
HGPPS 抗体
HGPS 抗体
RBIG1 抗体
Rbig1 抗体
Rig-1 抗体
RIG1 抗体
Rig1 抗体
Robo-3 抗体
Robo3 抗体
ROBO3 抗体
robo3 抗体
Robo3a 抗体
Robo3b 抗体
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