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ROBO1 产品

(Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured ROBO1 Categories

ROBO1 抗体

High quality antibodies with extensive validation data.

ROBO1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ROBO1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ROBO1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (10)
Cat. No. ABIN185537
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (1)
  • (5)
Cat. No. ABIN129621
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7270110
Quantity 100 μL
Datasheet Datasheet

Recommended ROBO1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973548
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959204
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730772
Quantity 96 tests
Datasheet Datasheet

Recommended ROBO1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318424
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964317
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731104
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ROBO1 Products

Fernando, Grisolia, Lu, Atkins, Smith: "Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 12, pp. 3942-3949, (2018) (PubMed).

Zhou, Thiery: "Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1." in: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2740-6, (2013) (PubMed).

Zhou, Geng, Chi, Zhang, Niu, Lan, Ma, Yang, Wang, Ding, Geng: "Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis." in: Cell research, Vol. 21, Issue 4, pp. 609-26, (2011) (PubMed).

Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: "Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain." in: Development (Cambridge, England), Vol. 133, Issue 11, pp. 2243-52, (2006) (PubMed).

Li, Wang, Chen, Liang: "[Auditory neuropathy in children(analysis of 14 cases)]." in: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, Vol. 19, Issue 1, pp. 19-21, (2006) (PubMed).

Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia." in: PLoS genetics, Vol. 1, Issue 4, pp. e50, (2005) (PubMed).

Wang, Xiao, Ding, Zhang, Yuan, Gui, Qian, Duan, Chen, Rao, Geng: "Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity." in: Cancer cell, Vol. 4, Issue 1, pp. 19-29, (2003) (PubMed).

Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: "Quantification of expression of netrins, slits and their receptors in human prostate tumors." in: International journal of cancer. Journal international du cancer, Vol. 103, Issue 3, pp. 306-15, (2002) (PubMed).

Hivert, Liu, Chuang, Doherty, Sundaresan: "Robo1 and Robo2 are homophilic binding molecules that promote axonal growth." in: Molecular and cellular neurosciences, Vol. 21, Issue 4, pp. 534-45, (2002) (PubMed).

Synonyms and alternative names related to ROBO1

roundabout guidance receptor 1 (ROBO1), roundabout guidance receptor 1 (Robo1), roundabout, axon guidance receptor, homolog 1 (Drosophila) (robo1), roundabout guidance receptor 1 L homeolog (robo1.L), roundabout guidance receptor 1 (robo1), AW494633, AW742721, DUTT1, dutt1, Gm310, MGC122264, ROBO1, roundabout, roundabout-1, SAX3, sax3

Protein level used designations for ROBO1

  • deleted in U twenty twenty
  • roundabout homolog 1
  • roundabout (axon guidance receptor, Drosophila) homolog 1
  • roundabout, axon guidance receptor, homolog 1 (Drosophila)
  • Roundabout1 protein
  • roundabout-1
  • roundabout 1
  • roundabout, axon guidance receptor, homolog 1
  • roundabout homolog 1-like
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