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RNH1 产品

(Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Categories

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover\; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010].

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Featured RNH1 Categories

RNH1 抗体

High quality antibodies with extensive validation data.

RNH1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RNH1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RNH1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
Cat. No. ABIN872914
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7440089
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN519824
Quantity 100 μg
Datasheet Datasheet

Recommended RNH1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962279
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1155735
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1155737
Quantity 96 tests
Datasheet Datasheet

Recommended RNH1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1318405
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318407
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2730897
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our RNH1 Products

Zechendorf, Gombert, Bülow, Frank, Beckers, Peine, Kotelis, Jacobs, Marx, Martin: "The Role of Ribonuclease 1 and Ribonuclease Inhibitor 1 in Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair." in: Journal of clinical medicine, Vol. 9, Issue 10, (2020) (PubMed).

Wang, Teferedegne, Shatzkes, Tu, Murata: "Data on the inhibition of RNase inhibitor activity by a monoclonal antibody as assessed by microfluidics-based RNA electrophoresis." in: Data in brief, Vol. 9, pp. 417-421, (2016) (PubMed).

Wang, Teferedegne, Shatzkes, Tu, Murata: "Endogenous RNase inhibitor contributes to stability of RNA in crude cell lysates: Applicability to RT-qPCR." in: Analytical biochemistry, Vol. 513, pp. 21-7, (2016) (PubMed).

Ascione, Rowlinson, Avolio, Katare, Meloni, Spencer, Mangialardi, Norris, Kränkel, Spinetti, Emanueli, Madeddu: "Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction." in: Stem cell research & therapy, Vol. 6, pp. 53, (2015) (PubMed).

Tang, Liu, Tian, Xu, Ren, Cui, Fan: "Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway." in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, (2014) (PubMed).

Spencer, Schwaderer, Eichler, Wang, Kline, Justice, Cohen, Hains: "An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract." in: Kidney international, Vol. 85, Issue 5, pp. 1179-91, (2014) (PubMed).

Rucksaken, Pairojkul, Pinlaor, Khuntikeo, Roytrakul, Selmi, Pinlaor: "Plasma autoantibodies against heat shock protein 70, enolase 1 and ribonuclease/angiogenin inhibitor 1 as potential biomarkers for cholangiocarcinoma." in: PLoS ONE, Vol. 9, Issue 7, pp. e103259, (2014) (PubMed).

Zhu, Das, Wu, Lee, Tan: "RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells." in: Oncogene, Vol. 33, Issue 12, pp. 1527-37, (2014) (PubMed).

Furia, Moscato, Calì, Pizzo, Confalone, Amoroso, Esposito, Nitsch, DAlessio: "The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei." in: FEBS letters, Vol. 585, Issue 4, pp. 613-7, (2011) (PubMed).

Synonyms and alternative names related to RNH1

ribonuclease/angiogenin inhibitor 1 (RNH1), ribonuclease/angiogenin inhibitor 1 (Rnh1), ribonuclease inhibitor (Tc00.1047053511893.10), ribonuclease inhibitor (Tc00.1047053507583.70), ribonuclease/angiogenin inhibitor 1 (rnh1), AW546468, C80305, im:7039360, RAI, RNH, Rnh, RNH1, Rnh1, si:ch211-213a13.3, wu:fd55g05

Protein level used designations for RNH1

  • placental RNase inhibitor
  • placental ribonuclease inhibitor
  • ribonuclease inhibitor
  • RNase inhibitor
  • ribonuclease/angiogenin inhibitor 1
  • uncharacterized protein rnh1
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