RNF103 产品
(Ring Finger Protein 103 (RNF103))
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The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011].
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Latest Publications for our RNF103 Products
: "Induction of kf-1 after repeated electroconvulsive treatment and chronic antidepressant treatment in rat frontal cortex and hippocampus." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 110, Issue 3, pp. 277-85, (2003) (PubMed).: "Identification of a novel gene with RING-H2 finger motif induced after chronic antidepressant treatment in rat brain." in: Biochemical and biophysical research communications, Vol. 278, Issue 1, pp. 150-7, (2000) (PubMed).
: "Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus." in: Biochemical and biophysical research communications, Vol. 231, Issue 2, pp. 481-7, (1997) (PubMed).
Synonyms and alternative names related to RNF103
ring finger protein 103 (RNF103), ring finger protein 103 (Rnf103), Adrg34, AW146237, AW212918, HKF-1, KF-1, kf-1, KF1, Kf1, ZFP-103, ZFP103, Zfp103Protein level used designations for RNF103
- E3 ubiquitin-protein ligase RNF103
- zinc finger protein 103 homolog
- zinc finger protein expressed in cerebellum
- mKF-1
- zfp-103
- zinc finger protein 103
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