RNASEL 产品
(Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
Categories
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Jul 2008].
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Featured RNASEL Categories
RNASEL 抗体
High quality antibodies with extensive validation data.
RNASEL ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RNASEL 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RNASEL 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN6146994
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
Cat. No.
ABIN7264894
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435379
Quantity
100 μL
Datasheet
Datasheet
Recommended RNASEL ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959174
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658504
Quantity
96 tests
Datasheet
Datasheet
Recommended RNASEL 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318166
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7402817
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397231
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RNASEL Products
: "RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation." in: Cell death and differentiation, Vol. 19, Issue 9, pp. 1470-81, (2012) (PubMed).: "Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements." in: Nucleic acids research, Vol. 40, Issue 16, pp. 7739-52, (2012) (PubMed).
: "Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation." in: Nucleic acids research, Vol. 37, Issue 11, pp. 3612-24, (2009) (PubMed).
: "Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 8035-43, (2009) (PubMed).
: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." in: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).
: "Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. ..." in: Nature genetics, Vol. 30, Issue 2, pp. 181-4, (2002) (PubMed).
: "Elevated levels of 2',5'-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 1, Issue 11, pp. 1421-8, (1999) (PubMed).
: "A bipartite model of 2-5A-dependent RNase L." in: The Journal of biological chemistry, Vol. 272, Issue 35, pp. 22236-42, (1997) (PubMed).
: "2-5A-dependent RNase molecules dimerize during activation by 2-5A." in: The Journal of biological chemistry, Vol. 270, Issue 8, pp. 4133-7, (1995) (PubMed).
Synonyms and alternative names related to RNASEL
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) (Rnasel), ribonuclease L (RNASEL), E230029I04Rik, PRCA1, RNS4Protein level used designations for RNASEL
- 2-5A-dependent RNAase
- 2-5A-dependent RNase
- 2-5A-dependent ribonuclease
- RNase L
- ribonuclease 4
- 2',5'-oligoisoadenylate synthetase-dependent
- interferon-induced 2-5A-dependent RNase
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