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RNASEH2A 抗体

(Ribonuclease H2, Subunit A (RNASEH2A))
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009].
RNASEH2A 抗体  (AA 1-299) RNASEH2A 抗体  (AA 1-299) RNASEH2A 抗体 (AA 1-299) (ABIN564592)

RNASEH2A 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G5-F5 unconjugated

RNASEH2A 抗体  (AA 1-299) RNASEH2A 抗体  (AA 1-299) RNASEH2A 抗体 (AA 1-299) (ABIN523945)

RNASEH2A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

RNASEH2A 抗体  (AA 1-301) RNASEH2A 抗体  (AA 1-301) RNASEH2A 抗体 (AA 1-301) (ABIN7445717)

RNASEH2A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

RNASEH2A 抗体 by 适用

Find RNASEH2A 抗体 for a variety of species such as anti-Human RNASEH2A, anti-Mouse RNASEH2A, anti-Rat RNASEH2A. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find RNASEH2A 抗体 validated for a specific application such as WB, IHC, ELISA, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find RNASEH2A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

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Find RNASEH2A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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RNASEH2A 抗体 by 克隆

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Find RNASEH2A 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RNASEH2A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (5)
Cat. No. ABIN564592
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN523945
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7445717
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Horse, Human, Monkey, Pig, Zebrafish (Danio rerio)
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN202188
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7269981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN630199
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN634223
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014281
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014280
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2778984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN7168107
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN564591
Quantity 50 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2778985
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168110
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7168109
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RNASEH2A 抗体

Zimmermann, Murina, Reijns, Agathanggelou, Challis, Tarnauskaitė, Muir, Fluteau, Aregger, McEwan, Yuan, Clarke, Lambros, Paneesha, Moss, Chandrashekhar, Angers, Moffat, Brunton, Hart, de Bono et al.: "CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. ..." in: Nature, Vol. 559, Issue 7713, pp. 285-289, (2019) (PubMed).

Wang, Wang, Feng, Shepherd, Zhang, Tang, Chen, Srivastava, McLaughlin, Navone, Hart, Chen: "Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition." in: Oncogene, (2018) (PubMed).

Bartsch, Damme, Regen, Becker, Garrett, Hölter, Knittler, Borowski, Waisman, Glatzel, Fuchs, Gailus-Durner, Hrabe de Angelis, Rabe: "RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation." in: Frontiers in immunology, Vol. 9, pp. 587, (2018) (PubMed).

Tresini, Warmerdam, Kolovos, Snijder, Vrouwe, Demmers, van IJcken, Grosveld, Medema, Hoeijmakers, Mullenders, Vermeulen, Marteijn: "The core spliceosome as target and effector of non-canonical ATM signalling." in: Nature, Vol. 523, Issue 7558, pp. 53-8, (2015) (PubMed).

Cuadrado, Michailidou, van Bodegraven, Jansen, Sluijs, Geerts, Couraud, De Filippis, Vescovi, Kuijpers, Hol: "Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3623-33, (2015) (PubMed).

Aliases for RNASEH2A 抗体

ribonuclease H2 subunit A (rnaseh2a) 抗体
ribonuclease H2 subunit A (RNASEH2A) 抗体
ribonuclease H2, large subunit (Rnaseh2a) 抗体
ribonuclease H2, subunit A (rnaseh2a) 抗体
ribonuclease H2 subunit A L homeolog (rnaseh2a.L) 抗体
ribonuclease H2, subunit A (RNASEH2A) 抗体
ribonuclease H2, subunit A (Rnaseh2a) 抗体
2400006P09Rik 抗体
AGS4 抗体
JUNB 抗体
RNASEHI 抗体
RNHIA 抗体
RNHL 抗体
zgc:56307 抗体
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