RNA Polymerase II 抗体
(RNA Polymerase II)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
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Recommended RNA Polymerase II 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IP
Validations
Cat. No.
ABIN7449805
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IP
Validations
Cat. No.
ABIN7450663
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP, ChIP
Validations
Cat. No.
ABIN7453315
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to RNA Polymerase II
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II)Protein level used designations for RNA Polymerase II
- DNA-directed RNA polymerase II subunit RPB7
- RNA polymerase II subunit B7
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