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RIPK3 产品

(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008].

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Featured RIPK3 Categories

RIPK3 抗体

High quality antibodies with extensive validation data.

RIPK3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RIPK3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RIPK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
  • (6)
Cat. No. ABIN6146964
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rat
Application WB, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN2777333
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (6)
Cat. No. ABIN3032449
Quantity 0.4 mL
Datasheet Datasheet

Recommended RIPK3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959068
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969854
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969855
Quantity 96 tests
Datasheet Datasheet

Recommended RIPK3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (2)
Cat. No. ABIN1318116
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318118
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509129
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RIPK3 Products

Duman, Alcigir, Yavuz: "Necroptosis mediated by receptor interacting protein kinase 3 as critical players in experimental congenital hypothyroidism related neuronal damage." in: Northern clinics of Istanbul, Vol. 8, Issue 5, pp. 472-478, (2021) (PubMed).

Allocca, Corrigan, Mazumder, Fake, Samson: "Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration." in: Science signaling, Vol. 12, Issue 568, (2020) (PubMed).

Piao, Miura, Miyake, Komazawa-Sakon, Koike, Shindo, Takeda, Hasegawa, Abe, Nishiyama, Mikami, Yagita, Uchiyama, Nakano: "Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation." in: The Journal of allergy and clinical immunology, Vol. 143, Issue 1, pp. 213-228.e10, (2019) (PubMed).

Chen, Pan, Li, Xu, Jin, Qian, Yan, Chen, Wang, Chen, Wang, Chen: "Inhibiting of RIPK3 attenuates early brain injury following subarachnoid hemorrhage: Possibly through alleviating necroptosis." in: Biomedicine & pharmacotherapy, Vol. 107, pp. 563-570, (2019) (PubMed).

Hou, Wang, Li, Li, Teng, Li, Wang, Chen, Huang: "The role of RIP3 in cardiomyocyte necrosis induced by mitochondrial damage of myocardial ischemia-reperfusion." in: Acta biochimica et biophysica Sinica, Vol. 50, Issue 11, pp. 1131-1140, (2019) (PubMed).

Yang, Joseph, Sun, Hoffmann, Thevissen, Offermanns, Strilic: "TAK1 regulates endothelial cell necroptosis and tumor metastasis." in: Cell death and differentiation, (2019) (PubMed).

Li, Gong, Wang, Li, Attri, Lewis, Kalil, Bhinderwala, Powers, Yin, Herring, Asara, Lei, Yang, Rodriguez, Yang, Green, Singh, Wen: "O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3." in: Immunity, Vol. 50, Issue 3, pp. 576-590.e6, (2019) (PubMed).

Podder, Guttà, Rožanc, Gerlach, Feoktistova, Panayotova-Dimitrova, Alexopoulos, Leverkus, Rehm: "TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma." in: Cell death and differentiation, (2019) (PubMed).

Goulielmaki, Assimomytis, Rozanc, Taki, Christodoulou, Alexopoulos, Zoumpourlis, Pintzas, Papahatjis: "DPS-2: A Novel Dual MEK/ERK and PI3K/AKT Pathway Inhibitor with Powerful Ex Vivo and In Vivo Anticancer Properties." in: Translational oncology, Vol. 12, Issue 7, pp. 932-950, (2019) (PubMed).

Font-Belmonte, Ugidos, Santos-Galdiano, González-Rodríguez, Anuncibay-Soto, Pérez-Rodríguez, Gonzalo-Orden, Fernández-López: "Post-ischemic salubrinal administration reduces necroptosis in a rat model of global cerebral ischemia." in: Journal of neurochemistry, (2019) (PubMed).

Synonyms and alternative names related to RIPK3

receptor interacting serine/threonine kinase 3 (RIPK3), receptor interacting serine/threonine kinase 3 S homeolog (ripk3.S), receptor-interacting serine-threonine kinase 3 (Ripk3), receptor interacting serine/threonine kinase 3 (Ripk3), 2610528K09Rik, AW107945, Hcyp2, RIP3, Rip3, RIPK3

Protein level used designations for RIPK3

  • receptor-interacting serine-threonine kinase 3
  • receptor-interacting serine/threonine-protein kinase 3-like
  • RIP-3
  • RIP-like protein kinase 3
  • receptor interacting protein 3
  • receptor-interacting protein 3
  • receptor-interacting serine/threonine-protein kinase 3
  • mRIP3
  • homocysteine respondent protein HCYP2
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