RIPK1 抗体
(Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.
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RIPK1 抗体 by 适用
Find RIPK1 抗体 for a variety of species such as anti-Human RIPK1, anti-Mouse RIPK1, anti-Rat RIPK1. The species listed below are among those available. Click on a link to go to the corresponding products.
RIPK1 抗体 by 应用范围
Find RIPK1 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.
RIPK1 抗体 by 抗体来源
Find RIPK1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
RIPK1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal RIPK1 抗体. Click on a link to go to the corresponding products.
RIPK1 抗体 by 克隆
Find RIPK1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular RIPK1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7441202
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441205
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (8)
Cat. No.
ABIN1490909
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (6)
Cat. No.
ABIN6146959
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN7193406
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IP
Validations
- (2)
Cat. No.
ABIN7177814
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7167470
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1490911
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1490913
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IP
Validations
- (2)
Cat. No.
ABIN7269886
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (2)
- (2)
Cat. No.
ABIN3042480
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (2)
- (2)
Cat. No.
ABIN3042930
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human
Application
WB
Validations
- (3)
Cat. No.
ABIN2792131
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032438
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN715016
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our RIPK1 抗体
: "Isolation and characterization of cluster of differentiation 9-positive ependymal cells as potential adult neural stem/progenitor cells in the third ventricle of adult rats." in: Cell and tissue research, Vol. 379, Issue 3, pp. 497-509, (2020) (PubMed).: "Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody." in: Cancer letters, Vol. 444, pp. 147-161, (2019) (PubMed).
: "Silencing of A20 Aggravates Neuronal Death and Inflammation After Traumatic Brain Injury: A Potential Trigger of Necroptosis." in: Frontiers in molecular neuroscience, Vol. 12, pp. 222, (2019) (PubMed).
: "Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1." in: International immunopharmacology, Vol. 77, pp. 105944, (2019) (PubMed).
: "Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression." in: Scientific reports, Vol. 9, Issue 1, pp. 17369, (2019) (PubMed).
: "TDP-43 accelerates age-dependent degeneration of interneurons." in: Scientific reports, Vol. 7, Issue 1, pp. 14972, (2018) (PubMed).
: "Targeting necroptotic cell death pathway by high-intensity interval training (HIIT) decreases development of post-ischemic adverse remodelling after myocardial ischemia / reperfusion injury." in: Journal of cell communication and signaling, (2018) (PubMed).
: "Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors." in: BMC cancer, Vol. 16, pp. 545, (2017) (PubMed).
: "Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis." in: Cell death & disease, Vol. 7, Issue 6, pp. e2287, (2016) (PubMed).
: "The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression." in: Nature, Vol. 532, Issue 7598, pp. 245-9, (2016) (PubMed).
Aliases for RIPK1 抗体
receptor interacting serine/threonine kinase 1 (RIPK1) 抗体receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1) 抗体
receptor interacting serine/threonine kinase 1 (Ripk1) 抗体
receptor interacting serine/threonine kinase 1 L homeolog (ripk1.L) 抗体
D330015H01Rik 抗体
Rinp 抗体
RIP 抗体
RIP1 抗体
Rip1 抗体
rip1 抗体
ripk1 抗体
xrip1 抗体
xRIP1beta 抗体
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